B1: Arthritis Flashcards
What happens to synovial fluid in response to inflammation?
Increases
Which cells produce cytokines during inflammation?
Synoviocytes and synovial macrophages
What are the three constituents of synovial fluid?
Plasma dialysate, hyaluronan, lubricin
What produces hyaluronan?
Synovial fibroblasts
What produces lubricin?
Chondrocytes
What happens if an injury reaches cancellous bone instead of just chondral or partial thickness?
Bone marrow involved so heals better- forms fibrocartilage and scars
What is a chondroprotectant?
Disease-modifying OA drugs e.g. hyaluronic acid
When is the best time to use a chondroprotectant?
In early disease e.g. synovitis
What is platelet rich plasma?
Autologous concentrated platelets
What is platelet rich plasma for?
Soft tissue injuries
Which vaccine can cause arthritis?
Feline calicivirus
Sulphonamides in which breed can cause arthritis?
Doberman or Weimaraner
