Azoles Flashcards
1
Q
what are azoles
A
antifungal agents
2
Q
azoles inhibit what
A
ergosterol synthesis
3
Q
what enzyme fo azoles inhibit
A
P450 enzyme
4
Q
what based activity
A
AUC/MIC
5
Q
what are the local activity
A
local candidiasis
oralpharyngeal thrush
cutaneous
6
Q
systemic activity of azoles are
A
fluconazole
candida spp
great CNS penetration
7
Q
what are some adveres effects of azoles
A
testosterone synthesis inhibition
liver dysfuntion
QTc prolongation
drug-drug interactions
