Azithromycin, Tranexamic Acid & Tamsulosin Supply Flashcards

1
Q

What are some risk factors for contracting a sexual infection?

A
  1. <25 years
  2. New sexual partner
  3. > 1 sexual partner in a year
  4. Lack of condom use
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When is the P and POM version of azithromycin supplied?

A

P: >16 years old

POM: privately or via NHS from GUM clinics, PGDs, family planning clinics, or the NCSP screening programme (<25years old)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the Clamelle chlamydia service?

A

A private service in which test kits are bought from the pharmacy. The patient then posts their kit to the laboratory.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is detected in the test kit for chlamydia?

A

It detects the nucleic acid of the chlamydia trachomatis bacterium.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What result is a person at risk of if they perform a test for chlamydia, using the test kit?

A

A false-positive or false-negative result can occur.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When should Clamelle 500mg tablets (P) be given?

A
  1. If the patient is >16 years old
  2. If they are asymptomatic
  3. If they tested positive
  4. To treat the infected persons partner
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What should pharmacists who are participating in the Clamelle chlamydia service must always do?

A

They should record any sale/supply of azithromycin on the Clamelle database.
The patients result should also be logged.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How can a patient avoid a false-negative result for chlamydia testing?

A

They should purchase a test kit 2 weeks after sexual intercourse.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How can a patient avoid a false-positive result for chlamydia testing?

A

They should not test again within 6 weeks after their treatment is completed, as their test can still show positive.
Dead DNA could be present which can cause this, otherwise the infection could be eradicated.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How long after chlamydia treatment should patients avoid having sexual intercourse?

A

Patient must not have sexual intercourse 1 week after their treatment is completed.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are OTC tranexamic acid 500mg tablets used for?

A

They are used to reduce heavy menstruation bleeding over several cycles in women.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Who is tranexamic acid 500mg OTC tablets given to?

A
  1. > 18 years old

2. With regular 21-35 day cycles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What risk can increase when taking tranexamic acid?

A

Since it is an anti-fibrinolysis agent, risks of clots can occur.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How many times should tranexamic acid 500mg tablets be taken daily?

A

It should be taken as 2 500mg tablets TDS, so 6 tablets a day until symptoms are alleviated.
Do not exceed 4 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When should you refer a patient if they wish to purchase tranexamic acid?

A
  1. <18 years old or >45 years old
  2. Women taking tranexamic acid for 3 cycles, but seeing no difference
  3. Breastfeeding/pregnant women
  4. Obese or diabetic women - higher risk of developing clots
  5. Patients taking oral contraceptives - can increase their clotting risk
  6. On warfarin or anticoagulants
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are some side effects of tranexamic acid?

A
  1. GI discomfort - nausea/diarrhoea - reduce dose in this case
  2. Visual disturbances - stop the medicine
  3. Allergic reactions - uncommon
17
Q

What is OTC 400mcg tamsulosin used for?

A

It is used to treat the symptoms of BPH (benign prostatic hyperplasia) in males 45-75 years old.
Also known as an enlarged prostate.

18
Q

What are the symptoms of BPH?

A
  1. Difficulty when urinating

2. Urinating for longer or more frequently

19
Q

What symptoms can differentiate between BPH & prostate cancer?

A

If the person is experiencing a fever or blood in the urine = could be a sign of prostate cancer.

20
Q

How many times a day is tamsulosin 400mcg given?

A

OD

21
Q

What type of drug is tamsulosin, and what other condition can it be used for?

A

It is an alpha blocker, also used as a last resort for resistant hypertension.

22
Q

What is the mechanism of action of tamsulosin?

A

It relaxes the smooth muscles in BPH, producing an increased urinary flow rate & an improvement in obstructive symptoms.

23
Q

What type of drug should not be given with tamsulosin?

A

Anticholinergics, since they produce opposite effects.

24
Q

What are some side effects of tamsulosin?

A
  1. Lowered BP - causing dizziness, headaches, fainting
  2. Blurred vision
  3. Dry mouth
  4. Oedema
  5. Palpitations
25
Q

What specific drugs can tamsulosin interact with?

A

They may react with other anti-hypertensive drugs, inducing an enhanced hypotensive effect.

26
Q

What information should you ask to supply tamsulosin?

A
  1. Age of patient (are they 45-75 years old)
  2. Their symptoms
  3. If their symptoms have been ongoing for 3 months - this MUST be met
  4. Any other medical conditions/medications being used
27
Q

How long should the initial tamsulosin treatment be?

A

2 weeks.

28
Q

If the patient is seeing an improvement in their BPH symptoms within 2 weeks of treatment, what should you do?

A

Supply a further 4 weeks of OTC tamsulosin.

29
Q

If the patients BPH symptoms have not been resolved after 2 weeks of treatment, what should you do?

A

Must refer.

30
Q

At what point should the patient visit their GP after starting tamsulosin treatment?

A

Within 6 weeks of starting their treatment.

31
Q

If a GP has confirmed a patient has BPH after 6 weeks OTC treatment, how many weeks of supply of tamsulosin can you give?

A

You can supply for a further 6 weeks.

32
Q

When should you refer a patient who wishes to purchase tamsulosin?

A
  1. Symptoms have been for <3 months
  2. Patient has had prostate surgery
  3. Patient has problems with their liver/kidneys/heart
  4. Pain on urination
  5. Fever
  6. Bloody/cloudy urine
  7. Leaking of urine (incontinence)
33
Q

What lifestyle advice can you give to a patient to alleviate symptoms of BPH?

A
  1. Avoid liquids before bed
  2. Reduce alcohol/caffeine intake
  3. Regular exercise
  4. Increase fruit/fibre
  5. Avoid cold/allergy medicines