Autonomic System Flashcards

1
Q

What two divisions are there in the autonomic nervous system?

A
  • sympathetic

- parasympathetic

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2
Q

What does the sympathetic division do?

A

Produces the responses seen in fright, fight or flight

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3
Q

What does the parasympathetic do?

A

Produces the changes in the resting, recovering or restorative state

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4
Q

What effects are seen in the sympathetic response?

A
  • pupils dilate
  • heart rate and force increases
  • vasodilation
  • decreased gut motility and secretion
  • saliva secretion reduced
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5
Q

What effects does the parasympathetic division have?

A

-pupils constrict
-gut motility and constriction increases
-saliva secretion increases
(-vessels not connected)
-decreased heart rate

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6
Q

What controls most visceral organs?

A

Both the parasympathetic and the sympathetic

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7
Q

What is craniosacral?

A

Brainstem and sacral spinal cord

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8
Q

What is thoracolumbar?

A

Thoracic and lumbar segments 1-3

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9
Q

How are ANS effectors regulated?

A

Neurons of the CNS regulate the effectors of the ANS through autonomic ganglia neurons

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10
Q

Which division of the ANS regulates cardiac output in the short term?

A

Sympathetic

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11
Q

What is the major structural difference between the parasympathetic and the sympathetic?

A
  • the parasympathetic preganglionic fibres are long (from the CNS) whereas the sympathetic are shorter
  • the parasympathetic postganglionic fibres are short (to the target) whereas sympathetic are short
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12
Q

What is the neurotransmitter at all autonomic ganglia?

A

Acetylcholine

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13
Q

What transmitter do parasympathetic postganglionic fibres release?

A

Acetylcholine

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14
Q

What transmitter do most sympathetic postganglionic fibres release?

A

Noradrenaline

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15
Q

What exceptions are there for sympathetic postganglionic fibre transmitters?

A

Acetylcholine: sweat glands, skeletal muscle blood vessels
NO: erectile tissue
Postulated: substance P, serotonin, ATP plus others

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16
Q

What do acetylcholine receptors also respond to?

A

Administered doses of nicotine and muscarine

17
Q

What receptors does the heart have for the sympathetic system?

A

Has beta-1 receptors to respond to noradrenaline to increase rate and force of contraction

18
Q

What does the parasympathetic system act on on the heart?

A

Acetylcholine acts on pacemaker (sino atrial node) and slows the inherent rhythm
(vagal tone)

19
Q

What chronotropic changes does the ANS have on the heart?

A
sympathetic = weak, positive
parasympathetic = strong, negative
20
Q

What inotropic changes does the ANS have on the heart?

A
sympathetic = strong, positive
parasympathetic = weak, negative
21
Q

What does the sympathetic division do to blood vessels?

A

alpha receptors on most organs mediate constriction

22
Q

Do blood vessels have a parasympathetic supply?

A

No, other than erectile tissue

23
Q

What does the sympathetic do to the lungs?

A

Beta-2 receptors mediate dilation of the airways

24
Q

What does the parasympathetic do to the lungs?

A

bronchioles constrict

25
What does salbutamol do to the lungs?
Selectively dilates bronchioles by activating beta-2 receptors
26
Why does salbutamol not affect the heart?
Heart has mainly beta-1 receptors
27
What effect does sympathetic have on the adrenal medulla?
Preganglionic fibre from CNS release acetylcholine which stimulates the release of adrenaline and noradrenaline into the blood to back up the sympathetic response
28
What effect does the parasympathetic have on the adrenal medulla?
None
29
What is hexamethonium?
An autonomic ganglion-blocking agent
30
What does hexamethonium do?
- removes sympathetic tone - abolishes parasympathetic response - parlous state