autonomic nervous system Flashcards
interoreceptors
internal receptors that include
1) chemoreceptors
2) mechanoreceptors
muscarinic are
present in plasma proteins of all effecters innervated by parasympathetic post ganglionic axons
adrenergic receptors for
most sympathetic receptors
The effects of sympathetic stimulation are
longer lasting and more widespread than the effects of parasympathetic stimulation
1) Sympathetic postganglionic acons diverge more extensively
2) Lack of stuff to get rid of norepinephrine
transport protein
they make the lipid soluble hormones temporarily water soluble thus increasing their solubility in blood
They retard passage of small hormone molecules through the filtering mechanism in the kidneys, thus slowing the rate of hormone loss in urine
Lipid soluble
diffuse from blood through the lipid bilayer of the plasma membrane
2) receptors in cytosol/nucleus.
The activated receptor hormone complex alters gene expression, turing specific genes of nuclear DNA on and off causing mRNA to synthesize a new protein on the ribosomes
Water soluble
integral transmembrane proteins in plasma membrane
hormone is first messenger
2nd messenger is cAMP
G protein, Adenylate cyclase turns ATP to cAMP in the cytosol, activates kinase, which phosphorylate a lot of shit
Number of hormones hypothalamus and pituitary secretes
9 v 7
Catecholamine
water soluble amines
Most outer layer
Mineralocorticoids
Zona fasciculata secrete glucocorticoids
weak androgens
Mineralocorticoids
regulates homeostasis of sodium ions and potassium ions
1) adjust blood pressure
2) adjust blood volume
help excrete H+ from urine to prevent acidosis
Glucocorticoids
protein break down in muscle fibers, liberation of amino acids for synthesis of new protein
turns lactic acid and amino acid to glucose
Lipolysis
break down of tryglyceride and release of fatty acids from adipose tissue to blood
Resistance to stress
sensitiuve to hormone causing vasoconstriction
Anti-inflammatory
retard tissue repair
slow healing,
useful for treatment of chronic inflammatory disorders
Depression of some immune responses
Glucocorticoids prescribed for organ transplant