autonomic drugs (to memorize the list!) Flashcards

This is JUST for memorizing the drugs, their class, and what receptors they activate. More info in the other slide decks!!!

1
Q

What are cholinergic agonists?

A

Substances that activate cholinergic receptors

Examples include acetylcholine, muscarine, pilocarpine, and bethanechol.

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2
Q

List three examples of cholinergic agonists.

A
  • Acetylcholine (M/N)
  • Muscarine (M)
  • Pilocarpine (M)
  • Bethanechol (M)
  • Physostigmine (AChE inhibitor)
  • Echothiophate (AChE inhibitor)
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3
Q

What is the function of adrenergic agonists?

A

Substances that activate adrenergic receptors

These can affect alpha and beta receptors.

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4
Q

List three examples of adrenergic agonists.

A
  • Norepinephrine (α1, α2, β1)
  • Epinephrine (α1, α2, β1, β2)
  • Phenylephrine (α1)
  • Clonidine (α2)
  • Dobutamine (β1)
  • Isoproterenol (β1, β2)
  • Albuterol (β2)
  • Tyramine (indirect)
  • Amphetamine (indirect)
  • Cocaine (indirect)
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5
Q

What are cholinergic antagonists?

A

Substances that block cholinergic receptors

An example is atropine.

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6
Q

List an example of a cholinergic antagonist.

A
  • Atropine (M)
  • D-Tubocurarine (NM)
  • Trimethaphan (NN)
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7
Q

What are adrenergic antagonists?

A

Substances that block adrenergic receptors

They can selectively block alpha or beta receptors.

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8
Q

List three examples of adrenergic antagonists.

A
  • Prazosin (α1)
  • Yohimbine (α2)
  • Metoprolol (β1)
  • Propranolol (β1, β2)
  • Butoxamine (β2)
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9
Q

Fill in the blank: Acetylcholine is a __________ agonist.

A

[cholinergic]

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10
Q

True or False: Epinephrine is an adrenergic agonist.

A

True

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11
Q

What is the role of AChE inhibitors?

A

They prevent the breakdown of acetylcholine, increasing its availability

Examples include physostigmine and echothiophate.

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12
Q

Fill in the blank: The drug __________ is a selective β1 adrenergic agonist.

A

[dobutamine]

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13
Q

What kind of drug is acetylcholine? What receptor(s) does it activate?

A

Cholinergic agonist (M/N)

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14
Q

What kind of drug is muscarine? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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15
Q

What kind of drug is pilocarpine? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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16
Q

What kind of drug is bethanechol? What receptor(s) does it activate?

A

Cholinergic agonist (M)

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17
Q

What kind of drug is nicotine? What receptor(s) does it activate?

A

Cholinergic agonist (N)

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18
Q

What kind of drug is physostigmine? What receptor(s) does it activate?

A

Cholinergic agonist (AChE inhibitor)

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19
Q

What kind of drug is echothiophate? What receptor(s) does it activate?

A

Cholinergic agonist (AChE inhibitor)

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20
Q

What kind of drug is atropine? What receptor(s) does it activate?

A

Cholinergic antagonist (M)

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21
Q

What kind of drug is Trimethaphan? What receptor(s) does it activate?

A

Cholinergic antagonist (Nn)

22
Q

What kind of drug is D-Tubocurarine? What receptor(s) does it activate?

A

Cholinergic antagonist (Nm)

23
Q

What kind of drug is norepinephrine? What receptor(s) does it activate?

A

Adrenergic agonist (a1, a2, b1)

24
Q

What kind of drug is epinephrine? What receptor(s) does it activate?

A

Adrenergic agonist (a1, a2, b1, b2)

25
Q

What kind of drug is phenylephrine? What receptor(s) does it activate?

A

Adrenergic agonist (a1)

26
Q

What kind of drug is clonidine? What receptor(s) does it activate?

A

Adrenergic agonist (a2)

27
Q

What kind of drug is dobutamine? What receptor(s) does it activate?

A

Adrenergic agonist (b1)

28
Q

What kind of drug is isoproterenol? What receptor(s) does it activate?

A

Adrenergic agonist (b1, b2)

29
Q

What kind of drug is albuterol? What receptor(s) does it activate?

A

Adrenergic agonist (b2)

30
Q

What kind of drug is tyramine? What receptor(s) does it activate?

A

Adrenergic agonist (indirect)

31
Q

What kind of drug is amphetamine? What receptor(s) does it activate?

A

Adrenergic agonist (indirect)

32
Q

What kind of drug is cocaine? What receptor(s) does it activate?

A

Adrenergic agonist (indirect)

33
Q

What kind of drug is prazosin? What receptor(s) does it activate?

A

Adrenergic antagonist (a1)

34
Q

What kind of drug is yohimbine? What receptor(s) does it activate?

A

Adrenergic antagonist (a2)

35
Q

What kind of drug is metoprolol? What receptor(s) does it activate?

A

Adrenergic antagonist (b1)

36
Q

What kind of drug is propranolol? What receptor(s) does it activate?

A

Adrenergic antagonist (b1, b2)

37
Q

What kind of drug is butoxamine? What receptor(s) does it activate?

A

Adrenergic antagonist (b2)

38
Q

What are the 4 cholinergic agonists that activate M receptors?

A
  • acetylcholine (M/N)
  • muscarine (M)
  • pilocarpine (M)
  • bethanechol (M)
39
Q

What are the 2 cholinergic agonists that activate N receptors?

A
  • nicotine (N)
  • acetylcholine (M/N)
40
Q

What are the 2 cholinergic agonists that are AChE inhibitors?

A
  • physostigmine
  • echothiophate
41
Q

What is the cholinergic antagonist that activates M receptors

42
Q

What is the cholinergic antagonist that activates Nm receptors?

Nm = Nicotinic (NM) receptors at the neuromuscular junction

A
  • D-Tubocurarine
43
Q

What is the cholinergic antagonist that activates Nn receptors?

Nn = Nicotinic (NN) receptors in autonomic ganglia

A
  • Trimethaphan
44
Q

What are the 3 indirect adrenergic agonists?

A
  • tyramine
  • amphetamine
  • cocaine
45
Q

What are the 3 adrenergic agonists that activate a1 receptors?

A
  • norepinephrine
  • epinephrine
  • phenylephrine
46
Q

What are the 3 adrenergic agonists that activate a2 receptors?

A
  • norepinephrine
  • epinephrine
  • clonidine
47
Q

What are the 4 adrenergic agonists that activate b1 receptors?

A
  • norepinephrine
  • epinephrine
  • dobutamine
  • isoproterenol
48
Q

What are the 3 adrenergic agonists that activate b2 receptors?

A
  • epinephrine
  • albuterol
  • isoproterenol
49
Q

What is the adrenergic antagonist that activates a1 receptors?

50
Q

What is the adrenergic antagonist that activates a2 receptors?

51
Q

What are the 2 adrenergic antagonists that activate b1 receptors?

A
  • metoprolol
  • propranolol
52
Q

What are the 2 adrenergic antagonists that activate b2 receptors?

A
  • propranolol
  • butoxamine