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My Sketchy Pharm > Autonomic - Beta Blockers > Flashcards

Autonomic - Beta Blockers Flashcards

1
Q

What is the suffix of many beta blockers and name some examples.

A

-“lol”, propranolol, metoprolol, atenolol

Conducted with the Brahm’s LOllaby sheet music

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2
Q

What sort of effects do beta blockers have on the heart?

A

Decreases cardiac contractility by antagonizing effect of beta 1 receptors throughout myocardium.

(Weak arm of piano player)

Suppress SA and AV nodes of heart

(Music notes of sheet music piano player is using)

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3
Q

What does inhibition of SA node activity lead to/

A

Bradycardia (low dangling heart watch of piano player)

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4
Q

What do beta blockers exacerbate and why?

A

Heart block due to excessive suppression of AV node conduction (the “door to remain unblocked” sign)

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5
Q

What are beta blockers useful in the management of and how?

A

Useful in the management of chronic stable angina by slowing heart rate, increasing diastolic filling, increasing contractility, and decrease cardiac oxygen consumption. (Angina anvil being played by xylophone player)

Management of hypertrophic obstructive cardiomyopathy (big obstructed heart bagpipe)

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6
Q

How do beta blockers treat angina?

A

Reducing myocardial oxygen damn (discarded oxygen line near xylophone player)

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7
Q

What are the beta 1 selective antagonists?

A

Atenolol, betaxlol, esmolol, acebutolol, metropolis (A-BEAM lights overhead)

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8
Q

What are beta 1 selective antagonists primarily used for?

A

Suppress adrenergic stimulation of heart (cardioselective) (A_BEAM spotlight on heart stage)

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9
Q

What are the cardioselective beta blockers used for?

A

Useful in acute treatment of MO and other acute coronary syndromes (ACS)

(Broken heart strings under the A-BEAM spotlight)

Useful in management of chronic heart failure to reduce excessive tachycardia and high catecholamines levels on the heart

(Failing heart balloon on the heart stage under A_BEAM spotlight)

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10
Q

What is carvedilol useful for?

A

Useful in management of chronic heart failure

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11
Q

What type of drug is carvedilol?

A

No selective beta blocker and alpha 1 blocker (extinguished alpha candle on carved candle holder)

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12
Q

What to beta blockers reduce the mortality for?

A

For chronic heart failure and post-MI (angel playing the harp on the heart stage)

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13
Q

What can be used to reduce cardiac remodeling by protecting heart from excess circulating catecholamines?

A

Beta blockers (Remodeling sign in the back)

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14
Q

What can beta blockers be used to treat?

A

Hypertension (high pressure pipes near the organ)

Migraine prophylaxis for episodic migraine (pounding head bell)

Sympathomimetic treatment of thyroid storm (big stormy bow tie on gong player)

Essential tumor (shaking baton)

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15
Q

What sort of effects do beta blockers have on the kidneys?

A

Inhibit production of renin by antagonizing beta 1 receptors at the juxtaglomerular apparatus (closed rain umbrella with blocked beta 1 bugle)

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16
Q

What type of drug is labetalol?

A

No selective beta blocker and alpha 1 blocker

17
Q

What can labetalol lead too?

A

Peripheral dilation (organ player with dilated sleeves)

18
Q

What does labetalol used for?

A

Hypertension in pregnancy (pregnant organist)

19
Q

What is labetalol used intravenously for and why?

A

Hypertensive emergency due to combine alpha and beta effects (emergency stop level on the hot pipes)

20
Q

What are useful in acute aortic dissection?

A

IV beta blockers (dissected organ pipe with ivy all around)

21
Q

What can be used full in the sympathomimetic treatment of a thyroid storm?

A

Propranolol, prednisone, propothyrouracil (the 3 P’s)

22
Q

Beta blockers have ________ properties.

A

Antiarrrhythmic (rhythm inducing record)

23
Q

What do nonselective beta blockers exacerbate and how?

A

Asthma and COPD by antagonizing beta 2 mediated bronchodilation (wheezing beta 2 tuba player)

24
Q

What can be used to treat glaucoma and how?

A

Topic no selective beta blockers such as timolol. They antagonize beta 2 receptors on ciliary epithelium to decrease aqueous humor production (draining the muted beta 2 tuba)

25
Q

What side effect does beta blockers cause in men?

A

Impotence (dropping trombone)

26
Q

What type of drug is acebutolol?

A

Selective beta 1 antagonist with partial agonist activity

27
Q

What type of drug in pin do lol?

A

Non selective beta blocker with partial agonist activity

28
Q

What should be avoided in patients with heart failure or history of MI?

A

Beta blockers with partial agonist activity such as pindolol and acebutolol (popping failing heart balloon with young people audience)

29
Q

What treats beta blocker toxicity?

A

Glucagon by stimulating heart via the glucagon receptors

My Sketchy Pharm (7 decks)

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