Autonomic - Beta Blockers

Question 1

What is the suffix of many beta blockers and name some examples.

Answer 1

-“lol”, propranolol, metoprolol, atenolol

Conducted with the Brahm’s LOllaby sheet music

Question 2

What sort of effects do beta blockers have on the heart?

Answer 2

Decreases cardiac contractility by antagonizing effect of beta 1 receptors throughout myocardium.

(Weak arm of piano player)

Suppress SA and AV nodes of heart

(Music notes of sheet music piano player is using)

Question 3

What does inhibition of SA node activity lead to/

Answer 3

Bradycardia (low dangling heart watch of piano player)

Question 4

What do beta blockers exacerbate and why?

Answer 4

Heart block due to excessive suppression of AV node conduction (the “door to remain unblocked” sign)

Question 5

What are beta blockers useful in the management of and how?

Answer 5

Useful in the management of chronic stable angina by slowing heart rate, increasing diastolic filling, increasing contractility, and decrease cardiac oxygen consumption. (Angina anvil being played by xylophone player)

Management of hypertrophic obstructive cardiomyopathy (big obstructed heart bagpipe)

Question 6

How do beta blockers treat angina?

Answer 6

Reducing myocardial oxygen damn (discarded oxygen line near xylophone player)

Question 7

What are the beta 1 selective antagonists?

Answer 7

Atenolol, betaxlol, esmolol, acebutolol, metropolis (A-BEAM lights overhead)

Question 8

What are beta 1 selective antagonists primarily used for?

Answer 8

Suppress adrenergic stimulation of heart (cardioselective) (A_BEAM spotlight on heart stage)

Question 9

What are the cardioselective beta blockers used for?

Answer 9

Useful in acute treatment of MO and other acute coronary syndromes (ACS)

(Broken heart strings under the A-BEAM spotlight)

Useful in management of chronic heart failure to reduce excessive tachycardia and high catecholamines levels on the heart

(Failing heart balloon on the heart stage under A_BEAM spotlight)

Question 10

What is carvedilol useful for?

Answer 10

Useful in management of chronic heart failure

Question 11

What type of drug is carvedilol?

Answer 11

No selective beta blocker and alpha 1 blocker (extinguished alpha candle on carved candle holder)

Question 12

What to beta blockers reduce the mortality for?

Answer 12

For chronic heart failure and post-MI (angel playing the harp on the heart stage)

Question 13

What can be used to reduce cardiac remodeling by protecting heart from excess circulating catecholamines?

Answer 13

Beta blockers (Remodeling sign in the back)

Question 14

What can beta blockers be used to treat?

Answer 14

Hypertension (high pressure pipes near the organ)

Migraine prophylaxis for episodic migraine (pounding head bell)

Sympathomimetic treatment of thyroid storm (big stormy bow tie on gong player)

Essential tumor (shaking baton)

Question 15

What sort of effects do beta blockers have on the kidneys?

Answer 15

Inhibit production of renin by antagonizing beta 1 receptors at the juxtaglomerular apparatus (closed rain umbrella with blocked beta 1 bugle)

Question 16

What type of drug is labetalol?

Answer 16

No selective beta blocker and alpha 1 blocker

Question 17

What can labetalol lead too?

Answer 17

Peripheral dilation (organ player with dilated sleeves)

Question 18

What does labetalol used for?

Answer 18

Hypertension in pregnancy (pregnant organist)

Question 19

What is labetalol used intravenously for and why?

Answer 19

Hypertensive emergency due to combine alpha and beta effects (emergency stop level on the hot pipes)

Question 20

What are useful in acute aortic dissection?

Answer 20

IV beta blockers (dissected organ pipe with ivy all around)

Question 21

What can be used full in the sympathomimetic treatment of a thyroid storm?

Answer 21

Propranolol, prednisone, propothyrouracil (the 3 P’s)

Question 22

Beta blockers have ________ properties.

Answer 22

Antiarrrhythmic (rhythm inducing record)

Question 23

What do nonselective beta blockers exacerbate and how?

Answer 23

Asthma and COPD by antagonizing beta 2 mediated bronchodilation (wheezing beta 2 tuba player)

Question 24

What can be used to treat glaucoma and how?

Answer 24

Topic no selective beta blockers such as timolol. They antagonize beta 2 receptors on ciliary epithelium to decrease aqueous humor production (draining the muted beta 2 tuba)

Question 25

What side effect does beta blockers cause in men?

Answer 25

Impotence (dropping trombone)

Question 26

What type of drug is acebutolol?

Answer 26

Selective beta 1 antagonist with partial agonist activity

Question 27

What type of drug in pin do lol?

Answer 27

Non selective beta blocker with partial agonist activity

Question 28

What should be avoided in patients with heart failure or history of MI?

Answer 28

Beta blockers with partial agonist activity such as pindolol and acebutolol (popping failing heart balloon with young people audience)

Question 29

What treats beta blocker toxicity?

Answer 29

Glucagon by stimulating heart via the glucagon receptors