Autonomic - Alpha Drugs

Question 1

What sort of drug is clonidine?

Answer 1

Alpha-2 agonist(Raul with claw weapon holding two lit candles)

Question 2

What sort of effects do alpha 2 agonists have on the CNS?

Answer 2

Inhibit sympathetic tone which can reduce blood pressure

Question 3

What can clonidine treat?

Answer 3

Hypertension to reduce cardiac output (high pressure pipes under the stage)

ADHD (distracting mirror)

Management of Tourette’s syndrome (Tourette’s marionette)

Question 4

What type of drug is alpha methyldopa?

Answer 4

Alpha 2 agonist

Question 5

What can alpha methyldopa be used to treat?

Answer 5

Hypertension

Question 6

What drug is primarily used to treat hypertension in pregnant women?

Answer 6

Alpha methyldopa

Question 7

What type of drug is tizanidine?

Answer 7

Alpha 2 agonist. A Central acting muscle relaxant (relaxing chair underneath the stage)

Question 8

What type of drug is phentalomine?

Answer 8

A reversible alpha 1 and alpha 2 receptor antagonist(phantom standing on chandelier with extinguished single and double candles)

Question 9

What is a negative side effect of alpha methyldopa?

Answer 9

Cause lupus like syndrome

Question 10

What does phentolamine cause?

Answer 10

Vasodilation (alpha 1 antagonist effect) (dilated sleeves of the shirt phantom is wearing)

Question 11

What type of drug is phenosybenzamine?

Answer 11

Irreversible alpha 1 and alpha 2 receptor antagonist (irreversible phoenix tattoo on phantom)

Question 12

What can alpha antagonists such as phentolamine be used to treat? What should be avoided in these cases and why?

Answer 12

Cocaine toxicity. Avoid beta blockers due to unopposed alpha vasoconstriction. (Person drink hot coca in the side)

Question 13

What natural products contain sympathomimetic tyramine?

Answer 13

Wine and aged cheese (person drinking wine and eating cheese on side)

Question 14

What prevents metabolism of tyramine? What can it lead to? What would you treat it with?

Answer 14

MAO inhibitors. Leads to hypertension crisis. Treat with alpha blockers such as phentolamine. (Mousetrap protecting the wine and cheese)

Question 15

What is a pheochromocytoma?

Answer 15

Catecholamines secreting tumor of the adrenal medulla (frozen colorful dessert)

Question 16

What do pheochromocytoma cause? What can you use to control blood pressure preoperatively and interoperatively?

Answer 16

Headaches, hypertension, palpitation, sweating. Alpha blockers such as phentolamine and phenoxynenzamine.

Question 17

What negative side effect do alpha antagonists cause?

Answer 17

Orthostatic hypertension (Tilt table on the stage)

Question 18

What reflex does aloha blocker induced hypotension cause?

Answer 18

Tachycardia (heart reflex hammer)

Question 19

What is the suffix of alpha 1 selective antagonists? What are examples of these drugs?

Answer 19

-“Osin”

Prazosin, terazosin, doxazosin, tamsulosin

Question 20

What does terazosin treat?

Answer 20

BPH. Relaxes smooth muscle in the urethra and prostate. (Bannister compressing on the opera singers but who is holding single extinguished alpha candle)

Question 21

What does prazosin treat?

Answer 21

PTSD. (Praying opera singer with dog tags)

Question 22

What type of drug is mirtazapine?

Answer 22

Atypical antidepressant with antagonist effects alpha 2 and other receptors (mirth and misery sign in corner)

Question 23

What does mirtazpine treat and how?

Answer 23

Depression by enhancing serotonin release (happy face, frowning mask)