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PCOL > AUTACOIDS > Flashcards

AUTACOIDS Flashcards

1
Q

Local hormone produced in tissues rather than in glands.

A

AUTACOIDS

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2
Q

Are locally acting hormone like substance, which originates from different tissue and produce intense biological activities near their site of synthesis or release.

A

AUTACOIDS

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3
Q

Classifications of autacoids:

A

AMINE AUTACOIDS
PEPTIDE AUTACOIDS
EICOSANOIDS

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4
Q

Biogenic amines:

A

(THREE CATECHOLAMINES)
DOPAMINE
NOREPINEPHRINE (NORADRENALINE)
EPINEPHRINE (ADRENALINE)

SEROTONIN
HISTAMINE

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5
Q

Eicosanoids:

A

LEUKOTRIENES
THROMBOXANES
PROSTAGLANDINS
PLATELET ACTIVATING FACTORS

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6
Q

Angiotensin
Kinins-bradykinin and kallikidin
Vasopressin
Vasoactive intestinal peptide
substance P
Slow reacting substance of anaphylaxis

A

POLYPEPTIDE

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7
Q

Is a biogenic substance with one or more anime groups.

A

BIOGENIC AMINE / AMINE AUTACOIDS

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8
Q

They are basic nitrogenous compounds formed mainly by decarboxylation of amino acids or by amination and transamination of aldehydes and ketones.

A

BIOGENIC AMINE

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9
Q

It regulate brain functions such as movement, behavior, emotions, temperature, blood pressure and endocrine secretions.

A

BIOGENIC AMINES

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10
Q

They are chemicals your immune system makes. They act like bouncers at a club.

A

HISTAMINE

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11
Q

They help your body get rid of something that’s bothering you — in this case, an allergy trigger, or “allergen.”

A

HISTAMINES

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12
Q

They start the process that hustles those allergens out of your body or off your skin. They can make you sneeze, tear up, or itch — whatever it takes to get the job done. They are part of you body’s defense system.

A

HISTAMINES

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13
Q

4 types of histamine receptors:

A

H1- RECEPTOR
H2- RECEPTOR
H3- RECEPTOR
H4- RECEPTOR

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14
Q

Drives cellular migration, nociception, vasodilation and bronchoconstriction.

A

H1-RECEPTOR

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15
Q

It modifies gastric acid secretion, airway mucus production, and vascular permeability.

A

H2-RECEPTOR

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16
Q

It plays an important role in neuro-inflammatory diseases.

A

H3- RECEPTOR

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17
Q

Other term for serotonin.

A

5-HYDROXYTRYPTAMINE

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18
Q

It is a monoamine neurotransmitter.

A

SEROTONIN OR 5-HYDROXYTRYPTAMINE

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19
Q

Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction.

A

SEROTONIN

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20
Q

It plays several roles in our body, including influencing learning, memory, happiness such as well as regulating body temperature, sleep, sexual behavior and hunger.

A

SEROTONIN

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21
Q

Produce in cells (tissue)

22
Q

Where is the autacoid located?

23
Q

Like hormone but not hormone

24
Q

Too much histamine can cause?

A

Harmful effect in our body

25
Life threatening allergic action
ANAPHYLAXIS
26
difficulty in breathing, bronchoconstriction in bronchi by H1
DYSPNEA
27
Effect of H1-receptor
ALLERGIC REACTION
28
Sleep disorder
NARCOLEPSY
29
Blood (WBC), Basophil, Eosinophils
H4-RECEPTOR
30
(Lack of enough serotonin is thought to play a role in depression, anxiety, mania and other health conditions.)
31
serotonin is almost exclusively produced in neurons originating in the raphe nuclei located in the midline of the brainstem. These serotonin-producing neurons form the largest and most complex efferent system in the human brain.
CENTRAL NERVOUS SYSTEM (CNS)
32
part of the brain where serotonin is?
BRAINSTEM
33
Where are 5-HT receptors located?
POST-SYNAPTIC ENTERIC AND SENSORY NEURONS ENTERIC NEURONAL MEMBRANES VAGUS GASTRIC ENDOCRINE GLANDS AND IN THE CNS
34
Where is most serotonin found?
GUT (INTESTINES)
35
About ____ of serotonin is found in the cells lining your gastrointestinal tract.
90%
36
About ___ of serotonin is produced by our brain.
10%
37
Is 5-HT the same as serotonin?
YES, BECAUSE SERONININ IS ALSO KNOWN AS 5-HYDROXYTRYPTAMINE (5-HT)
38
primarily affects mood, promoting feelings of well-being. It also affects appetite, sleep cycles and pain perception.
SEROTONIN / 5-HYDROXYTRYPTAMINE (5-HT)
39
What causes a lack of serotonin?
AGE-RELATED HEALTH AND BRAIN CHANGES CHRONIC STRESS A LACK EXPOSURE TO NATURAL LIGHT LACK OF PHYSICAL ACTIVITY
40
6 symptoms of low serotonin levels:
• MEMORY PROBLEMS • FEELING LOW • CRAVING SWEET FOODS • HAVING PROBLEM SLEEPING • FEELING BAD ABOUT YOURSELF • INCREASED LIBIDO (SEXUAL DESIRE)
41
The most widely used class of antidepressant drugs is commonly referred to as?
TRICYCLIC ANTIDEPRESSANTS
42
Is a mechanism to enhance blood flow to areas of the body that are lacking oxygen/or nutrients.
VASODILATION
43
(The vasodilation' "causes a decrease in systemic vascular resistance (SVR) and an increase in blood flow, resulting in a reduction of blood pressure.)
44
are involved in the synthesis of serotonin and other neurotransmitters.
FOLIC ACID AND VITAMIN B12
45
has been found in many patients who have depression or decreased attention, concentration, and memory.
VITAMIN B12 DEFICIENCY
46
H2 BLOCKERS
• CIMETIDINE • FAMOTIDINE • NIZATIDINE • RANITIDINE
47
H3 BLOCKERS:
• CLOBENPROPIT • CIPROXIFAN • CONESSINE • BETAHISTINE • PITOLISANT • ABT - 239 • A-349 • 821 • THIOPERAMIDE
48
treatment for psychiatric disorder or cognitive disorder
THIOPERAMIDE
49
H4 BLOCKERS
VUF- 6002
50
orally active and inhibits the activity of both mast cell and eosinophils in vivo, and has anti-inflammatory and anti-hyperallergic effects
VUF- 6002

PCOL (5 decks)

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