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Neuropharmacology > Atypical Neurotransmitters > Flashcards

Atypical Neurotransmitters Flashcards

1
Q

What happens in classical neurotransmission?

A

Lecture 6, slide 2

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2
Q

Give some examples of classical neurotransmitters?

A

Lecture 6, slide 3

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3
Q

Give examples of atypical neurotransmitters

A

Lecture 6, slide 4

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4
Q

Describe a purinergic synapse and what happens at one.

A

Lecture 6, slide 6

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5
Q

What are some functions of adenosine and ATP in the brain

A

Lecture 6, slide 7

  • sleep and arousal
  • pain
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6
Q

Give examples of neuropeptides.

A

Lecture 6, slide 9

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7
Q

Describe what generally happens at a peptidergic synapse. What does low frequency depolarisation lead to? What does high frequency depolarisation lead to?

A

Lecture 6, slide 10

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8
Q

Discuss the opioid family of peptides and the genes that encode them.

A

Lecture 6, slide 11

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9
Q

What effects do opioids produce at synapses? What functions are associated with opioid neurotransmission?

A

Lecture 6, slide 12

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10
Q

Give examples of tachykinins. How are they synthesised, what are their receptors, localisation and function and pharmacology?

A

Lecture 6, slide 13

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11
Q

What are some therapeutic applications of small molecule drugs that target peptidergic CNS synapses?

A

Lecture 6, slide 14

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12
Q

What is retrograde transmission? Give examples of retrograde messengers.

A

Lecture 6, slide 16

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13
Q

What happens at an endocannabinoid synapse?

A

Lecture 6, slide 18

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14
Q

What are some therapeutic uses of drugs that target the endocannabinoid system?

A

Lecture 6, slide 19

  • appetite
  • emesis
  • pain
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15
Q

How is NO synthesised at synapses? What are its cellular effects, possible role in LTP and excitotoxicity?

A

Lecture 6, slide 22

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16
Q

What are neurotrophic factors?

A

Lecture 6, slide 24

17
Q

What do neurotrophic factors signal through? What modes of transmission do neurotrophic factors have? What are some functions of neurotrophic factors?

A

Lecture 6, slide 25

Neuropharmacology (8 decks)

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