Atypical antipsychotics counselling Flashcards

1
Q

Check for contraindications

A
  • Hepatic impairment
  • Phaeochromocytoma
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2
Q

How the treatment works

A
  • Schizophrenia is thought to be caused by problems with dopamine receptors in your brain
  • Atypical antipsychotics work by blocking these receptors
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3
Q

Treatment course and how it’s taken

A
  • Tablet injection or depot injection every 2-4 weeks
  • Dose built up over a week or two
  • Dose adjusted depending on response
  • Can take several days or weeks to work
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4
Q

Monitoring required

A
  • Before treatment, at 3 months, 12 months, then annually: pulse, BP, weight, waist circumference, ECG, HbA1C, fasting glucose, lipid profile, prolactin
  • Weight checks weekly for 6 weeks
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5
Q

Side effects

A
  • Anti-dopaminergic (tardive dyskinesia, tremor, movement disorders)
  • Anti-cholinergic (constipation, dry mouth)
  • Anti-histaminergic (weight gain, dizziness, drowsiness)
  • Anti-adrenergic (Hypotension)
  • Neuroleptic malignant syndrome (high fever and muscle rigidity)
  • Agranulocytosis (clozapine)
  • Withdrawal
  • Hyperglycaemia and diabetes
  • Hyperprolactinaemia (sexual dysfunction, menstrual disturbance, galactorrhoea etc)
  • Prolonged QT
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