Atropine

Question 1

Atropine Drug Class

Answer 1

Anticholinergic

Question 2

Atropine Action

Answer 2

• Antagonises parasympathetic effect of acetylcholine on muscarinic receptors resulting in:
• Increased heart rate
• Reducing smooth muscle contraction causing pupillary dilation, reduced GI motility and reduced bladder tone
• Blocks exocrine gland activity causing decreased salivary, bronchial, gastric, and sweat secretions

Question 3

Atropine Adverse Effects

Answer 3

• Dry mouth
• Blurred vision
• Tachycardia
• Nausea and vomiting
• Hyperthermia
• Dysrhythmias
• Agitation, delirium, hallucinations, seizures, and coma may occur in high doses
• Urinary retention

Question 4

Atropine Contraindications

Answer 4

Nil

Question 5

Atropine Preparations

Answer 5

• 600mcg in 1mL, diluted with 5mL NaCl to make 600mcg in 6mL

- 2mg in Atropen autoinjector

Question 6

Atropine Use

Answer 6

• Bradycardia
• Organophosphate poisoning
• Nerve agent poisoning