ATP and ETS- Bikman Flashcards

1
Q

What is beta oxidation?

A

It is breaking down fatty acid chains into acetyl-CoA, FADH2, and NADH for every two carbons

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2
Q

What are the irreversible enzymes of the Kreb cycle?

A

citrate synthetase, isocitrate dehydrogenase, alpha ketogluterate dehydrogenase

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3
Q

What enzymes in the Kreb cycle are inhibited by NADH, ATP, or GTP?

A

isocitrate dehydrogenase and alpha ketogluterate

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4
Q

What steps in the Kreb cycle make CO2 and NADH?

A

isocitrate dehydrogenase and alpha ketogluterate

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5
Q

What steps in the Kreb cycle make FADH2?

A

succinate synthetase

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6
Q

What steps in the Kreb cycle make only NADH?

A

malate dehydrogenase

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7
Q

What steps in the Kreb cycle make ATP?

A

succinyl-coA synthetase

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8
Q

What other derivatives can enter the Kreb cycle?

A

ketones, amino acids, fatty acids, glucose

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9
Q

What are the products of one cycle of the Krebs cycle?

A

3 NADH, 1 FADH2, and 1 ATP

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10
Q

Where does the Krebs cycle take place?

A

In the mitochondrial matrix

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11
Q

Where does ETS take place?

A

In the mitochondrial inner membrane

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12
Q

How many H+ does ATP synthase need to make one ATP?

A

4 H+

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13
Q

How many H+ does NADH allow into the intermembrane space during ETS? How many ATP does this make?

A

10 H+; 2.5 ATP

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14
Q

How many H+ does FADH2 allow into the intermembrane space during ETS? How many ATP does this make?

A

6 H+; 1.5 ATP

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15
Q

What does ANT and VDAC do in the ETS?

A

It transfers ATP and ADP from the cytosol into the mitochondrial matrix

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16
Q

What does the malate-aspartate shuttle do?

A

Supplies complex 1 in the ETS with more NADH

17
Q

What does the glycerol 3-P shuttle do?

A

Supplies complex 2 in the ETS with more FADH2