Absorption and Metabolism of Carbs - Rosenberg Flashcards

1
Q

What are the major carbohydrates?

A

starch, lactose and sucrose

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2
Q

Starches contain what kind of monosaccharides?

A

alpha- D- glucose

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3
Q

Amylose has what kind of linkages?

A

alpha-1,4 bonds

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4
Q

Amylopectin has what kind of linkages?

A

alpha-1,4 and alpha-1,6 bonds

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5
Q

Sucrose has what kind of monosaccharides?

A

alpha-D-glucose and a beta-D-fructose

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6
Q

What bond does sucrose contain?

A

alpha, beta- 1,2 bond

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7
Q

Lactose has what kind of monosaccharides?

A

beta-D-galactose and alpha-D-glucose

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8
Q

Lactose had what kind of bond?

A

Beta-1,4 bond

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9
Q

Trehalose is a sugar found in insects. What kind of monosaccharides are found in trehalose?

A

2 alpha-D-glucose

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10
Q

Salivary amylase and Pancreatic amylase both break down the same thing. What does it break down and what are its products?

A

Both of the amylases break down amylose and amylopectin into maltose, maltotriose, oligosaccharides, and alpha-dextrins. It can break interior alpha-1,4 bonds

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11
Q

What are the enzymes that break down sugars in the stomach?

A

There are none

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12
Q

What needs to be secreted in the intestines to allow for enzymes to work efficiently?

A

Bicarbonate. Secretin tells the pancreas to secrete a solution of bicarbonate to neutralize stomach acid.

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13
Q

What occurs in the luminal phase of digestion of carbs?

A

pancreatic amylase is secreted and breaks down interior alpha-1,4 bonds

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14
Q

What occurs in the membrane phase of digestion of carbs?

A

Lactase, Trehalase, Glucoamylase, and Sucrase-Isomaltase all break down sugars into monosaccharides from the intestinal villi membrane

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15
Q

What bond does Lactase break?

A

Beta-1,4 bonds

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16
Q

What bond does Trehalase break?

A

Alpha, Alpha-1,1 bonds

17
Q

What bond does Glucoamylase break?

A

Exterior alpha-1,4 bonds from the non-reducing ends

18
Q

What bond(s) does Sucrase-Isomaltase break?

A

Alpha-1,4, Alpha-1,6, and Alpha, Beta-1,2 bonds

19
Q

What makes fiber different from other dietary carbohydrates?

A

It cannot be broken down by human enzymes. It needs to be broken down by colon bacteria

20
Q

What are the products of metabolizing fiber?

A

Short chain fatty acids, gas, and lactic acid

21
Q

Where does absorption of monosaccharides occur?

A

In the epilthelial lining of the small intestine

22
Q

Which transporter is Sodium Dependent?

A

SGLT
SGLT1- intestines
SGLT2- kidneys

23
Q

What does SGLT transport and how does it transport it?

A

SGLT transports glucose and galactose across the epithelial membrane. It uses Na gradient because the sugars are going from a low to high concentration

24
Q

Where is the site of GLUT1

A

GLUT1’s site is in the RBCs

25
Q

Where is the site of GLUT2 and what does it transport?

A

GLUT2 transports galactose, fructose, and glucose in the liver, pancreas and the intestines

26
Q

Where is the site of GLUT3?

A

GLUT3 is the major transporter of the CNS

27
Q

Where is the site of GLUT4 and what makes it special?

A

GLUT4 is in skeletal muscles, cardiac muscles, and adipose tissue. It is insulin dependent

28
Q

Where is the site of GLUT5 and what makes it special?

A

GLUT5 is in the intestines and in sperm. It transports fructose into epithelial cells.

29
Q

What are the symptoms of lactose intolerance?

A

Abdominal bloating, cramps, gas, diarrhea