Absorption and Metabolism of Carbs - Rosenberg Flashcards

1
Q

What are the major carbohydrates?

A

starch, lactose and sucrose

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2
Q

Starches contain what kind of monosaccharides?

A

alpha- D- glucose

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3
Q

Amylose has what kind of linkages?

A

alpha-1,4 bonds

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4
Q

Amylopectin has what kind of linkages?

A

alpha-1,4 and alpha-1,6 bonds

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5
Q

Sucrose has what kind of monosaccharides?

A

alpha-D-glucose and a beta-D-fructose

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6
Q

What bond does sucrose contain?

A

alpha, beta- 1,2 bond

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7
Q

Lactose has what kind of monosaccharides?

A

beta-D-galactose and alpha-D-glucose

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8
Q

Lactose had what kind of bond?

A

Beta-1,4 bond

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9
Q

Trehalose is a sugar found in insects. What kind of monosaccharides are found in trehalose?

A

2 alpha-D-glucose

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10
Q

Salivary amylase and Pancreatic amylase both break down the same thing. What does it break down and what are its products?

A

Both of the amylases break down amylose and amylopectin into maltose, maltotriose, oligosaccharides, and alpha-dextrins. It can break interior alpha-1,4 bonds

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11
Q

What are the enzymes that break down sugars in the stomach?

A

There are none

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12
Q

What needs to be secreted in the intestines to allow for enzymes to work efficiently?

A

Bicarbonate. Secretin tells the pancreas to secrete a solution of bicarbonate to neutralize stomach acid.

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13
Q

What occurs in the luminal phase of digestion of carbs?

A

pancreatic amylase is secreted and breaks down interior alpha-1,4 bonds

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14
Q

What occurs in the membrane phase of digestion of carbs?

A

Lactase, Trehalase, Glucoamylase, and Sucrase-Isomaltase all break down sugars into monosaccharides from the intestinal villi membrane

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15
Q

What bond does Lactase break?

A

Beta-1,4 bonds

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16
Q

What bond does Trehalase break?

A

Alpha, Alpha-1,1 bonds

17
Q

What bond does Glucoamylase break?

A

Exterior alpha-1,4 bonds from the non-reducing ends

18
Q

What bond(s) does Sucrase-Isomaltase break?

A

Alpha-1,4, Alpha-1,6, and Alpha, Beta-1,2 bonds

19
Q

What makes fiber different from other dietary carbohydrates?

A

It cannot be broken down by human enzymes. It needs to be broken down by colon bacteria

20
Q

What are the products of metabolizing fiber?

A

Short chain fatty acids, gas, and lactic acid

21
Q

Where does absorption of monosaccharides occur?

A

In the epilthelial lining of the small intestine

22
Q

Which transporter is Sodium Dependent?

A

SGLT
SGLT1- intestines
SGLT2- kidneys

23
Q

What does SGLT transport and how does it transport it?

A

SGLT transports glucose and galactose across the epithelial membrane. It uses Na gradient because the sugars are going from a low to high concentration

24
Q

Where is the site of GLUT1

A

GLUT1’s site is in the RBCs

25
Where is the site of GLUT2 and what does it transport?
GLUT2 transports galactose, fructose, and glucose in the liver, pancreas and the intestines
26
Where is the site of GLUT3?
GLUT3 is the major transporter of the CNS
27
Where is the site of GLUT4 and what makes it special?
GLUT4 is in skeletal muscles, cardiac muscles, and adipose tissue. It is insulin dependent
28
Where is the site of GLUT5 and what makes it special?
GLUT5 is in the intestines and in sperm. It transports fructose into epithelial cells.
29
What are the symptoms of lactose intolerance?
Abdominal bloating, cramps, gas, diarrhea