Absorption and Metabolism of Carbs - Rosenberg Flashcards
What are the major carbohydrates?
starch, lactose and sucrose
Starches contain what kind of monosaccharides?
alpha- D- glucose
Amylose has what kind of linkages?
alpha-1,4 bonds
Amylopectin has what kind of linkages?
alpha-1,4 and alpha-1,6 bonds
Sucrose has what kind of monosaccharides?
alpha-D-glucose and a beta-D-fructose
What bond does sucrose contain?
alpha, beta- 1,2 bond
Lactose has what kind of monosaccharides?
beta-D-galactose and alpha-D-glucose
Lactose had what kind of bond?
Beta-1,4 bond
Trehalose is a sugar found in insects. What kind of monosaccharides are found in trehalose?
2 alpha-D-glucose
Salivary amylase and Pancreatic amylase both break down the same thing. What does it break down and what are its products?
Both of the amylases break down amylose and amylopectin into maltose, maltotriose, oligosaccharides, and alpha-dextrins. It can break interior alpha-1,4 bonds
What are the enzymes that break down sugars in the stomach?
There are none
What needs to be secreted in the intestines to allow for enzymes to work efficiently?
Bicarbonate. Secretin tells the pancreas to secrete a solution of bicarbonate to neutralize stomach acid.
What occurs in the luminal phase of digestion of carbs?
pancreatic amylase is secreted and breaks down interior alpha-1,4 bonds
What occurs in the membrane phase of digestion of carbs?
Lactase, Trehalase, Glucoamylase, and Sucrase-Isomaltase all break down sugars into monosaccharides from the intestinal villi membrane
What bond does Lactase break?
Beta-1,4 bonds
What bond does Trehalase break?
Alpha, Alpha-1,1 bonds
What bond does Glucoamylase break?
Exterior alpha-1,4 bonds from the non-reducing ends
What bond(s) does Sucrase-Isomaltase break?
Alpha-1,4, Alpha-1,6, and Alpha, Beta-1,2 bonds
What makes fiber different from other dietary carbohydrates?
It cannot be broken down by human enzymes. It needs to be broken down by colon bacteria
What are the products of metabolizing fiber?
Short chain fatty acids, gas, and lactic acid
Where does absorption of monosaccharides occur?
In the epilthelial lining of the small intestine
Which transporter is Sodium Dependent?
SGLT
SGLT1- intestines
SGLT2- kidneys
What does SGLT transport and how does it transport it?
SGLT transports glucose and galactose across the epithelial membrane. It uses Na gradient because the sugars are going from a low to high concentration
Where is the site of GLUT1
GLUT1’s site is in the RBCs