Astrocytic tumors

Question 1

Astrocytic tumors are divided into 3 groups. Which?

Answer 1

1. diffuse, adult type gliomas
2. diffuse pediatric type gliomas
3. circumscribed gliomas.

Question 2

The adult-type diffuse gliomas are grouped in 2. Which?

Answer 2

1. Astrocytoma, IDH mutant: WHO CNS grade 2 to 4
2. Glioblastoma, IDH wt: WHO CNS grade 4

Question 3

Circumscribed astrocytic gliomas are divided in 6 groups.

Answer 3

1. pilocystic astrocytoma: gr 1
2. high-grade astrocytoma with piloid features: not graded but poor prognosis.
3. pleomorphic xanthoastrocytoma: gr 2-3
4. Subependymal giant cell astrocytoma: gr 1
5. Choroid glioma: gr 2
6. Astroblastoma, MN1 altered - grade not assigned.

Question 4

There is another group of astrocytoma that behaves differently. what?

Answer 4

Spinal astrocytoma

Question 5

Jag rör ofta ihop astrocytom och gliom. Varför?

Answer 5

Gliom kan utgöras av vilken typ av gliaceller som helst, dvs
* Astrocyter
* Oligodendrocyter
* Ependymal celler
* Microglia.
Dessutom, i perifera nervsystemet:
* Schwann celler
* satellitceller

Astrocytom är absolut vanligast av gliomen.