ASTRINGENTS Flashcards
______ is a chemical compound that tends to shrink or constrict body tissues and precipitate the protein and astringent form protective layer on the surface.
An astringent substance
astringents are able to reduce the cell permeability due to what?
due to their protein action
______ are usually applied to damaged skin topically or to the mucous membrane of GIT including the mouth.
Astringents
___ reduces local edema, exudation, and inflammation.
Astringent
Characteristics of an astringent:
- Affect only the superficial layer. Reduce cellular permeability.
- Make the surface mechanically strong, decrease exudation.
- Protect from external irritation.
- Possess local styptic and local antiseptic action.
- May interfere with the function of pain receptors. The pain relieving action is mild.
- Constrict the blood vessels to stop bleeding.
Types of Astringents:
• Vegetable astringents
• Metallic Astringents
• Miscellaneous
Tannic acid, Gallic acid
Vegetable astringents
Aluminium salts: Alum [KAl(SO4)2•12H2O], Aluminium chloride (AlCl3), Auminium acetate
Zinc salts: Zinc chloride (ZnCl2), Zinc sulfate (ZnSO4)
Ferric chloride (FeCl3)
Strontium chloride
Silver nitrate (AgNO3)
Copper sulfate (CuSO4)
Metallic Astringents
Very cold water, Alcohol
Miscellaneous
Indications:
Swollen, inflamed and/or leaky tissues.
They are used to treated diarrhea or dysentery.
During leukorrhea (thick white/yellowish vaginal discharge)
During minor bleeding like Menorrhagia, Hemorrhoids.
They promote healing process.
They decrease sweating and possess deodorant properties.
Mild astringent solutions are used in the relief of such minor skin irritations as those resulting from
superficial cuts, allergies, insect bites, or fungal infections such as athlete’s foot.
Zinc sulfate chemical formula
ZnSO4
As a mineral ZnSO4·7H2O is known as ______.
Goslarite
zinc sulfate appearance, odor, and taste
white powder or white granular in nature; odorless; astringents and metallic taste
When heated over 6800 C, zinc sulfate decomposes into ______ and _______, both which are hazardous.
sulfur dioxide gas and zinc oxide fume
how many percent is there zinc sulfate for ophthalmic purposes?
0.25%