Asthma and COPD Questions Flashcards
MOA for asthma drugs for Asthma and COPD
Tiotropium bromide: muscarinic receptor antagonist
a. True.
MOA for asthma drugs for Asthma and COPD
Montelukast: beta 2 adrenoceptor agonist
b. False. Leukotriene receptor antagonist
MOA for asthma drugs for Asthma and COPD
Formoterol: beta 2 antagonist
c. False. Agonist
MOA for asthma drugs for Asthma and COPD
Theophylline: inhibition of phosphodiesterase
d. True
MOA for asthma drugs for Asthma and COPD
Budesonide: inhibit gene transcription
e. True. CS
Asthma drugs:
a. Theophylline increases risk of bradycardia in the elderly
a. False. Tachycardia
b. A short course of oral prednisone (7-14 days) is used to treat acute exacerbations of asthma
b. False. ?
c. Inhaled beclomethasone increases the risk of oropharyngeal candidiasis
c. True
d. Oral salbutamol causes tremor
d. True
e. Smoking increases plasma concentrations of theophylline
e. False. Decreases increased P450 activity
Asthma and COPD drugs adverse effects:
a. Tiotropium bromide: tremor
a. False: Muscarinic antagonist dry mouth, bitter taste, paradoxical bronchoconstriction, urinary retention and constipation (less likely)
b. Montelukast churg-strauss vasculitis
b. True (but rare)
c. Oral salbutamol: sedation
c. False.
d. Theophylline: seizures
d. True
e. Fluticasone: sore throat
e. True. ICS
Drugs used in the treatment of Asthma and COPD
a. Formoterol has a faster onset of action than salbutamol
a. False. Formoterol is LABA and salbutamol is a SABA
b. Montelukast is used in the management of exercise induced asthma
b. True
c. Theophylline clearance is reduced in the elderly
c. True
d. Tiotropium bromide causes dry mouth
d. True. Muscarinic antagonist
e. IV hydrocortisone is used in the treatment of acute severe ashtma
e. True
Asthma/ COPD
a. Inhaled ipratropium bromide has a longer duration of action than tiotropium bromide
a. False, tiotropium is long acting
b. Montelukast is used in the treatment of exercise induced asthma
b. True
c. Inhaled salbutamol has a slower onset of action than inhaled salmeterol
c. False
d. Salmeterol is preferred to salbutamol in an acute attack of asthma
d. False
e. Inhaled beclomethasone causes oropharyngeal candidiasis
e. True
Drug used in the management of asthma and COPD
a. Fluticasone is b2 receptor agonist
a. False. CS
b. Clearance of theophylline is reduced in patients over the age of 55
b. True
c. Inhaled ipratropium bromide causes dry mouth as a side effect
c. True
d. Montelukast causes nightmares as an adverse effect
d. True
e. Salbutamol causes bradycardia as an adverse effect
e. False. Tachycardia
