Anti-histamines Questions Flashcards
Histamine-1-receptor antagonists
a. Desloratadine has a shorter duration than chlorpheniramine
a. False. 3rd gen have the longest duration of action
b. Diphenhydramine increases tremors in patients with Parkinson’s
b. False, the antimuscarinic effects of diphenhydramine are used to treat Parkinson’s
c. Diphenhydramine causes constipation as an adverse effect
c. True, antimuscarinic effects cause constipation
d. Chlorpheniramine is used to treat rhinitis caused by rhinovirus
d. True, antimuscarinic effects dry up nasal secretions
e. Promethazine causes drowsiness as an adverse effect
e. True
Antihistamines: therapeutic indications:
a. Desloratadine: allergic rhinitis
a. True.
Antihistamines: therapeutic indications:
b. Diphenhydramine: insomnia
b. True
Antihistamines: therapeutic indications:
c. Doxylamine: dry cough
c. True. Antimuscarinic effects
Antihistamines: therapeutic indications:
d. Cyclizine: nausea and vomiting
d. True. Cyclcizine is indicated for labyrinthe disorders, as an anti-emetic and for motion sickness
Antihistamines: therapeutic indications:
e. Loratadine: motion sickness
e. False.
The following histamine-1-receptor antagonists are correctly matched with their clinical use:
a. Cyclizine: nausea and vomiting
a. True
The following histamine-1-receptor antagonists are correctly matched with their clinical use:
b. Promethazine: treatment of pruritis
b. True (think of anaesthetics)
The following histamine-1-receptor antagonists are correctly matched with their clinical use:
c. Diphenhydramine: treatment of insomnia
c. True
The following histamine-1-receptor antagonists are correctly matched with their clinical use:
d. Loratadine: vertigo
d. False
The following histamine-1-receptor antagonists are correctly matched with their clinical use:
e. Desloratadine: cough suppressant
e. False. Need antimuscarinic properties
Antihistamines:
a. Desloratadine causes more sedation than doxylamine
a. False. Gen 3 vs 1
b. Cyclizine has a longer duration of action than loratadine
b. False: Gen 1 vs 2
c. Desloratadine is used to treat chronic urticaria
c. True. 2nd or 3rd gen antihistamine
d. Loratadine is used to treat allergic rhinitis
d. True
e. Diphenhydramine decreases tremor in patients with Parkinsonism
e. True. Antimuscarinic effects
The following antihistamines cause sedation
a. diphenhydramine
a. True
The following antihistamines cause sedation
b. promethazine
b. True
The following antihistamines cause sedation
c. cyclizine
c. True
The following antihistamines cause sedation
d. loratadine
d. False
The following antihistamines cause sedation
e. chlorpheniramine
e. True
