Asthma Flashcards
Are anti-histamines bronchodilators?
No
What would be the first step in treating asthma?
Use a bronchodilator for occasional relief
(Short acting beta 2 adrenoceptor agonists
What are salbutamol and terbutaline and when are they used in asthma?
Short acting beta 2 adrenoceptor agonists (SABA)
Where are beta 2 adrenoceptors located?
In the lungs
What do salbutamol and terbutaline do?
Dilate bronchioles
Immediate relief
What are side effects of short acting beta 2 adrenoceptor agonists?
Tolerance
Tachycardia
Hypokalaemia
Tremor
What would you add into treatment on top of short acting beta 2 adrenoceptor agonists if they were being used more than twice a week or at night?
A regular inhaled corticosteroid
What do inhaled corticosteroids do?
Prevent inflammation and an immune response
Reduced IL-2
Reduced mast cells (IL-3)
What are fluticasone, budesonide, beclamethasone examples of?
Inhaled corticosteroid
How long do inhaled corticosteroids take to work?
Slow
3-7 days
What can be a side effect of inhaled corticosteroids?
Oral thrush
What are salmeterol and and formoterol exam0es of?
Regular inhaled long acting beta 2 agonists
When would you use salmeterol?
2 times daily
What two treatments can you use together for moderate asthma?
Regular inhaled corticosteroid and regular inhaled long acting beta 2 agonist
What do leukotriene receptor antagonists do?
Inhibit lung inflammation
Montelukast, zarfirlukast
