Assisting in the Analysis of Blood Flashcards
A group of related proteins that function as antibodies.
- They are found in plasma and other body fluids.
immunoglobulins
a measurement of the percentage of packed RBCs in a volume of blood.
- Normal HET varies with age and general 36%-52%
hematocrit
what do lower hematocrit levels indicate?
anemia or bleeding
what do higher hematocrit levels indicate?
dehydration or polycythemia vera
A disorder characterized by an abnormal increase in the number of red blood cells in the blood.
polycythemia vera
A deficiency of hemoglobin in the blood.
- It is accompanied by a reduced number of red blood cells, pale skin, weakness, and shortness of breath, among other symptoms.
anemia
The layer of white blood cells and platelets that separates red blood cells and plasma in a centrifuged sample of whole blood.
buffy coat
Helps in the destruction of parasites and fungi
Eosinophil
Helps in the destruction of allergens
Basophil
Destroy foreign substances by producing antibodies
- B and T cells combined are the second most abundant WBC in the blood, about 20%–40%
Lymphocyte
produce specific antibodies against a particular antigen
B cells
The oxygen-carrying pigment of red blood cells.
hemoglobin
what is the normal hemoglobin range in a female
12-16 g/dL
what is the normal hemoglobin range in a male
14-18 g/dL
fragments of a larger cell called a megakaryocyte.
- The smallest of the formed elements in the peripheral blood and assists with blood clotting.
Platelets
Plasma is made up of approx. what % of blood volume ?
55%
lab test that measures the rate at which RBC’s gradually separate from plasma and settle at the bottom of a calibrated tube in one hour.
- General indicator/marker for inflammation - ex: RA,lupus,TB
ESR
test that measures the time it takes blood to form a fibrin clot
PT
higher RBC count causes :
Dehydration
performed by hematology
H&H: (Hemoglobin & Hematocrit)
Pale red blood cells. Lacking color.
hypochromic
The study of the form, shape, and structure of an organism or a cell.
morphology
blood test that analyzes the ability of the kidneys to perform their function
Blood urea nitrogen BUN
what panel ?
CPX, Troponin I, Troponin T
Cardiac panel
what panel ?
TSH, T3, T4
Thyroid panel
what panel ?
sodium, potassium, chloride
Electrolyte panel
what panel ?
creatine, BUN, Uric acid, glucose
Renal panel
what panel ?
ALP, GGT, AST, ALT, LDH
Liver panel
HDL, LDL, ratios, glucose
Cholestech LDX analyzer
an instrument used to separate blood cells from plasma
centrifuge
name used to describe an immature neutrophil
band / stab cell
RBC that is larger than normal
Macrocytic
Where are all blood cells formed?
bone marrow
Thrombocytes are formed elements that assist with __________ in the blood system.
clotting
When testing blood, the physician orders a hemoglobin A1C test.
Which diagnosis is the physician trying to confirm?
diabetes
The normal hematocrit percentage in a male is:
42 to 52%.
The normal hematocrit percentage in an infant is:
37 to 41%.
Low microhematocrit values can indicate:
anemia
When a patient presents with pain, which test is ordered to diagnose inflammation in the body?
ESR
Which result is a normal hemoglobin level for a female patient?
12 to 16 g/dL
What is the optimal level for LDL (low-density lipoprotein) when screening for cholesterol?
less than 100 mg/dL
Patients with type _____ blood are considered universal donors.
O
A good wedge smear should cover how much of the slide?
½ to ¾ of the slide
also described as glycosylated hemoglobin (sugar-coated hemoglobin).
- Glycosylated hemoglobin is the result of glucose irreversibly binding to the hemoglobin molecules in the RBCs.
Hemoglobin A1C
what level should Fasting Blood Glucose (FBG) be at
less than 100 mg/dL.
or “diff,” in the CBC is to analyze and count the types of WBCs found in a sample of blood.
- The differential can be manually performed using a stained blood smear and a microscope, or with an automated instrument.
differential
Which test is used to determine renal function?
Creatinine
What do elevated: CPK levels indicate?
Possible MI
a normal adult WBC count
4500 = 11,000
Platelets are fragments of a larger cell called a _____
megakaryocyte
The buffy coat is what color?
White
Increases in RBC count are found in patients who are _____
dehydrated
Which component of the complete blood count is not necessary to calculate the red cell indices?
Differential
A properly prepared wedge smear has blood covering _____
½ to 3/4 of the slide.
_____ results are an indicator of inflammation in the body.
high ESR
Which department of the lab performs H&H tests?
Hematology
A blood test that analyzes the ability of the kidneys to perform their function is the
BUN
_______ is a component of a cardiac panel
Troponin
What hormones are detected in a thyroid panel?
Thyroxine T4 Triiodothyronine Thyroid Stimulating hormone (TSH)
______ is measured to monitor Diabetes
Hemoglobin A1
HDL transports _____
cholesterol
Which leukocyte is associated with allergies?
Eosinophil
T cells and B cells are a subclassification of
Lymphocytes
Buffy Coat is found in the center of the tube after blood is
centrifuged
Which test measures the time it takes blood to form a fibrin clot?
P7
_____ have large, dark, blue-black granules and contain histamine.
Basophil
If there is no time for the lab to perform a type and cross-match, which blood would be administered?
Type O
Which test is used for the initial screening of a patient for diabetes type 2?
Fasting blood glucose (FBG)
_____ are the formed elements in the peripheral blood and is a cell fragment that assists with clotting.
Platelets
What test may indicate conditions such as acute and chronic infections, RA, TB, Hepatitis, cancer, MM, aner lupus erythematosus?
ESR
Medical term for higher number of platelets
thrombocytosis
This instrument used to separate blood cells from plasma?
centrifuge
A low micro hematocrit is seen in patients with what condition?
Anemia
______ is a condition that produces an unusually large number of RBC.
Polycythemia vera
The name used to describe an immature neutrophil?
Band or Stab cell
Larger than normal RBC is described as ________
macrocytic
Rh-positive babies born to mothers with Rh-negative blood are at risk of developing ____
HDN
_______ is a test that determines long-range blood glucose control.
Hemoglobin A1C
T/F
- Blood type O is considered the “universal donor” because no anti-A or anti-B are found in plasma.
False
T/F
The lifespan of an erythrocyte is approximately 120 days.
True
T/F
If a capillary tube is not plugged, it must be filled with a special clay before centrifugation.
True
T/F
-B cells produce specific antibodies against a particular antigen
True
T/F
Lavender topped tubes are used for routine CBC tests.
True
T/F
-the WBC is lowest in newborns and highest in adults.
False
T/F
-Increases in the WBC count that are not related to disease are seen in pregnant women and individuals icing extreme stress.
True
T/F
- the shape of RBCs shows significant variation from normal, the alteration in shape is called thrombocytopenia
False
T/F
-RBC with normal amounts of hemoglobin is said to be hyperchromic.
False
T/F
-AST and ALT testing is done to monitor potential liver damage in patients receiving stain drugs.
True
What does hematocrit reading indicate?
Total blood volume