Aspirin

Question 1

Aspirin Schedule

Answer 1

2

Question 2

Aspirin Pregnancy Category

Answer 2

D (3rd trimester)

Question 3

Aspirin MoA (3) - COX enzymes, Prostaglandins, Thromboxane

Answer 3

1. Irreversibly blocks COX1 and COX 2 enzymes
2. Inhibits synthesis of prostaglandins E2 ( antipyretic and analgesic effect)
3. Inhibits synthesis of thromboxane T2 ( prevents aggregation of platelets)

Question 4

Aspirin Uses (5 = 4 x A’s + A)

Answer 4

ACS (Acute Coronary Syndrome)
4 things
- Analgesic
-Antipyretic
- Anti-inflammatory
- Anti-platelet aggregation

Question 5

Aspirin Contraindications (5 - CABS + H)

Answer 5

C - Chest pain if SBP>160 (associated w/psychostimulant OD)
A - Active bleeding peptic ulcers
B - bleeding disorders
S - Suspected dissecting aortic aneurysm

H - Hypersensitivity

Question 6

Aspirin Precautions (3 - PAP)

Answer 6

P - Peptic ulcer
A - Asthma
P - Patients on anticoagulants

Question 7

Aspirin Side effects (4 - HING)

Answer 7

H - Heartburn
I - Increased bleeding
N - Nausea
G - GI bleeding