Aspects of Disease Flashcards
What is an Abnormal Body Process with or without characteristic signs?
Disease
The Father of Pathology discovered that disease starts where?
Molecular/Cellular Level
Is Apoptosis generally pathological or physiological?
It is generally physiological BUT can be pathological also!
List the 4 aspects of Disease…
- Etiology 2. Pathogenesis 3. Morphological and Molecular Changes 4. Clinical Manifestation
What is Etiology?
The cause of disease.
If there is more than 1 etiology causing disease, it is termed….
Multifactorial
List examples of Genetic/Intrinsic Etiology…
Inherited Mutations, Disease-Associated Gene Variants, and polymorphisms
List examples of Acquired/Extrinsic Etiology…
Infectious, Nutritional, Chemical, and Physical
Define Prognosis…
What is expected to happen to the patient…what you tell the client.
Define Pathogenesis…
The sequence of events from initial stimulus to the ultimate expression of disease in response of cells and tissues to the etiology (Also encompasses the mechanisms of disease development .)
List the 5 key characteristics veterinarians must consider when describing a Morphological Diagnosis (Mdx)
- location (organ tissue) 2. distribution (focal, multifocal, locally extensive, diffuse) 3. severity (mild, moderate, severe) 4. duration/time (acute, chronic) 5. nature (degenerative, inflammatory, neoplastic)
Define Etiologic Diagnosis…
the more definitive diagnosis that names the SPECIFIC cause(s) of the disease
List the 5 Pathological Processes…
- degenerative/necrosis 2. inflammation and repair 3. tissue deposits and pigmentations 4. circulatory disorders 5. disorder of growth (adaptation vs. neoplasia vs. malformation)
Define Pathognomonic…
characteristic or indicative of a SPECIFIC disease
Define Necrosis…
the stage of dying; a form of cell injury resulting in premature death of cells in living tissue by autolysis
