Artherosclerosis

Question 1

Predisposing factors

Answer 1

Diet
Hypertension
Cigs
Diabetes

Question 2

Definition of artherosclerosis

Answer 2

Hardening of arteries

Thickening of wallls and loss of elasticity

Question 3

3 types

Answer 3

Rather Keris is - affects intima of elastic and muscular arteries

Monckbergs medial sclerosis- calcification of media of muscular arteries

Arteriosclerosis- proliferation or hyaline thickening of walls of small arteries/ arterioles

Question 4

In small arteries artheromas are

Answer 4

Occlusive and compromise blood flow causing Ishaemic injury

Question 5

Arthescloris -> thrombosis ->

Answer 5

Unstable angina

Question 6

Stages of artheromous plaque

Answer 6

1 lipid present in macrophage in intima

2 lipid present in macrophage and smooth muscle

3 fibrous plaque

4 complex plaque

Question 7

Effect of artherosclerosis on major arteries

Answer 7

Narrowing ofvascular lumina

Results in ischaemia of tissues perfumed by these vessels

Question 8

Artherosclerosis can lead to

Answer 8

Infarct

Provides site for thrombosis and embolism

Weakening wall of a vessel causing aneurysm or rupture

Question 9

What can be deleted in 40% OF PLAQUES

Answer 9

Fibrin

Question 10

When is there a significant risk to sudden death

Answer 10

When artheromous plaque occluded 70% of cross sectional area