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Toxicity of this city > Arsenic > Flashcards

Arsenic Flashcards

1
Q

What is the first symptom of arsenic poisoning?

A

Severe gastroenteritis

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2
Q

What dose of arsenic can be lethal?

A

> 1mg/kg

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3
Q

What is it found in?

A

Earths crust/the ground! Semiconductors | Glass | pesticides | wood | herbal remedies

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4
Q

Why are arsenics in seafood non-toxic?

A

They are not metabolised to free arsenic

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5
Q

What is the deadliest form of arsenic?

A

Arsine gas: generated when arsenic mixes with an acid

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6
Q

What clinical syndromes can occur?

A

Encaphlopathy/seizures
Acute cardiomyopathy/prolonged QT
Bone marrow suppression
Alopecia

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7
Q

Chronic toxicity?

A

Cutaneous lesions - hyperpigmentation
Mees lines on nails
Peripheral neuropathy

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8
Q

What bedside test can be used?

A

Spot urinary arsenic

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9
Q

Treatment?

A

Chelation using oral/NG DMSA 10mg/kg orally TDS
Can be used for all heavy metal intoxications including LEAD
SAFE drug and can be given as an outpatient if otherwise stable

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Toxicity of this city (11 decks)

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