Arrhythmias - Torsades de Pointes Flashcards

1
Q

ESSENCE

A

Polymorphic ventricular tachycardia characterised by sinusoidal and cyclic alterations on ECG

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2
Q

AETIOLOGY

Risk factors

A
  • Low magnesium
  • Low potassium
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3
Q

AETIOLOGY

Common causes

A
  • Familial
  • Drugs (remember ABCDE)
    • Class 1A antiarrhythmics
    • Class III antiarrhythmics
    • antiBiotics
    • antipsyChotics
    • antiDepressants
    • antiEmnetics
    • Diuretics
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4
Q

PROGNOSIS

Long term

A

Typically resolves spontaneously but may degenerate into ventricular fibrillation and death

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5
Q

CLINICAL FEATURES

Symptoms

A
  • Palpitations
  • Dizziness
  • Syncope
  • Symptoms may be triggered by stress
  • Sudden cardiac death
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6
Q

CLINICAL FEATURES

Signs

A
  • Tachycardia
  • Pallor
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7
Q

INVESTIGATIONS

First choice

A
  • Labs
    • U&Es
  • ECG
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8
Q

ECG findings

A
  • If in sinus rhythm
    • Prolonged QT interval
    • Pathological U waves
  • If in episode
    • Change in polarity of QRS around the isoelectric line
    • Sinusoidal waveform
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9
Q

MANAGEMENT

Options

A
  • Conservative
    • Discontinue all QT prolonging drugs
  • Medical
    • Magnesium sulfate
    • B-antagonists
  • Operative
    • Pacing
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10
Q

Discontinue all QT prolonging drugs indication

A

All patients

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11
Q

Magnesium sulfate indicates

A

All patients

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12
Q

B-antagonist indication

A

Long term therapy for patients with congenital long QT syndrome

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13
Q

Pacing indications

A
  • Medical failure
  • Typically for patients with congenital long QT syndrome
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