ARF Flashcards
What is the main stay of Symptomatic ARF TXT
ASA Children 80-100mg/kg/D Adults 4-8g/D
What age do you see RF
5-15yo
Is there a specific TXT for ARF rash?
No
Antibodies tested for in RF
- ASO (antistreptolysin O)
- Anti-DNase B 3.ASTZ (antistreptozyme)
Prolonged PRI is due to
Early carditis
What new murmur may a RF pt develop
Transient (MC) MR or AR
What type of Rx prophylaxis is continuously used?
PCN G benzathine (IM) PCN V (PO) Sulfadiazine IF allergic
Sydenham’s chorea is
Neurologic D/O of abrupt rapid involuntary nonrhythmic movement (Stops when sleeping)
Prophylaxis for RF w/carditis and w/out valvular disease?
Prophylaxis for 10 years or until pt is 21yo
When do you DC TXT
Until ALL S/S are gone and ESR/CRP are NL
TXT of carditis
TXT HF, Heart block, or valve repair or replacement for nonresponsive HF
DX of ARF requires
Strep evidence \+ (Jones) MAJ 2 MAJ 1 + 2 Min
Evidence of GAS inf is
POS antibodies (elevated/rising) or POS Cx/Rapid test
What is the most severe sequela of ARF
Rheumatic heart DZ
Valvular damage from RF is also known as
Rheumatic heart disease
MAJ JONES critera includes
J - Joints (Migratory polyarthritis)
O - Carditis
N - nodules (SQ)
E - Erythema marginatum
S - Sydenham’s chorea
Dx tests for RF include
Strep A Rapid/CX, Antibody titer CRP and ESR
CXR (Cardiomegaly or HF)
EKG (heart blocks)
Carditis presents as
Early in Dz New murmur Pancarditis and friction rub Cardiomegaly
Prophylaxis for RF w/carditis and persistent valve disease?
Prophylaxis for 10 years or until pt is 40yo Sometimes lifelong
What is secondline med if unresponsive to ASA
CCS (prednisone)
Erythema Marginatum
Rash that’s non-pruritic/non-painful eruption raised or flat patches on trunk and prox extremities
RF subQ nodules are
Firm painless nodules on wrists, elbows, knees and achilles lasting for 1-2 weeks
RF non-specific S/S
Fever
Joint aches Abdominal pain
Weakness
Fatigue
Migratory Poly-arthritis is
Severe pain in large joints of extremities w/ rubor, calor, tumor, dolor - lasting <4wks