Approach to Therapeutics Flashcards

1
Q

What are the broad therapeutic categories used in treating inflammatory arthritis?

A

1) NSAID’s

2) Disease Modifying anti Rheumatic Drugs (DMARDS)

3) Biologics

4) Corticosteroids

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2
Q

What are the general aims of treatment of the patient with RA?

A
  • Retard disease progression
  • Modify disease activity
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3
Q

What is the importance of early and aggressive managment in RA?

A
  • obtaining optimal outcomes in RA
  • improve symptoms and prevent joint damage
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4
Q

What are the benefits, risks and cost effectiveness of each of the main classes of drugs used to treat RA patients?

A

Biologic DMARD’s:

Benefits - work rapidly when used with Methotrexate, well tolerated

Risks - Some associated toxicities, infection

Cost - High

Corticosteroids:

Benefits - short term benefit

Risks - long-term toxicity

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5
Q

Whate 2 drugs are most commonly used in the treatment of RA?

A

1 - Methotrexate

2 - Sulfasalazine

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