APP 6 Flashcards
What is the endocrine system made up of? (2)
Clusters of epithelial cells that secrete hormones (messenger molecules)
What is the endocrine system for, and how does it do what it does? (3)
To maintain homeostasis - the messenger molecules make cells do things that keep conditions in the body relatively constant when things around are changing
Why are the glands of the endocrine system called ductless glands? (3)
because they don’t release their hormones into ducts – they are secreted into the tissues and enter the blood vessels
Why don’t all cells respond to all hormones? (1)
Because only certain cells have receptors for certain hormones
What happens when hormones reach the target tissue cells? (1)
They change what those cells are doing
What are the 2 ways by which hormones can change what a cell is doing?
Fat soluble hormones switch on the gene(s) in the DNA that contain the ‘instructions’ for the ‘job’
Water soluble hormones bind to a receptor and act as enzymes that make the cell do its job
Which other system, besides the endocrine system, maintains homeostasis? (1)
Nervous system (esp ANS)
What are the differences between the way the nervous and endocrine systems work? (6)
Neurotransmitters act very locally, and act very quickly for a very short time
Hormones act over a wide area, work more slowly, and last for a long time
What 3 types of stimulus can make glands secrete hormones? (3)
Nervous signals
Chemical changes in blood
Other hormones
How is the secretion of most hormones controlled, and what is the one exception to this? (2)
Negative feedback, oxytosin
Which two major systems does the hypothalamus control? (2)
NS and endocrine system
What do most of the hormones released by the hypothalamus do? (1)
Make the pituitary glands release their hormones
How do the hormones secreted by the hypothalamus get to the anterior pituitary? (1)
Via hypophyseal portal system
How do secretions of the hypothalamus get to the posterior pituitary? (1)
Neurones that start in the hypothalamus reach down into the posterior pituitary and release neurotransmitters, NOT hormones, which are stored there
Which two hormones are released from the posterior pituitary? (2)
ADH and Oxytosin
What is the stimulus that causes human growth hormone to be released from the anterior pituitary gland? (1)
Low blood sugar
What effect does too much human growth hormone have on children and adults? (2)
Giantism and acromegaly
What effect does too little growth hormone have on children?(1)
Pituitary Dwarfism (Lorain-Levi Syndrome)
Where is the thyroid gland? (1)
Around the larynx
Which two hormones does the thyroid gland release? (2)
T3 is triiodothyromine (has 3 Iodine atoms)
T4 is thyroxine (has 4 iodine atoms)
What is the main effect of T3 and T4 on body cells
Allows them to access more oxygen so they can produce more energy (inc BMR)
List 5 symptoms of hyperthyroidism (5)
Increased heart rate, Fatigue, Weight loss, Heat intolerance, Xs sweating, Hyperactive reflexes, Tremor exophthalmos, Nervousness, Polydipsia (thirst), Increased appetite, Shortage of breath, Swollen neck (enlargement of thyroid gland - goitre), Bulging eyes, (eyelids retract and eye muscles inflamed – exopthalmos)
What is the main hormone secreted by the testes and what does it do? (3)
Testosterone
Regulates sperm production,
Stimulates production and maintenance of male characteristics eg beard growth, deepening of the voice
What are the two main hormones produced by the ovaries? (2)
Oestrogen, progesterone
What are the 4 main things the female sex hormones do? (4)
Regulate the menstrual cycle
Maintain pregnancy
Prepare mammary glands for lactation
Establish and maintain the female body shape
What does prolactin do in women? (1)
Prolactin initiates and maintains milk production by the mammary glands
Where do the glucocorticoid hormones come from, and what is their overall effect? (3)
Adrenal cortex
Mobilising energy, responding to stress
What causes Cushing Syndrome ? (1)
Oversecretion of glucocorticoids
What is the main effect of Melanin Stimulating Hormone o skin? (3)
It causes specialised skin cells called melanocytes to produce the pigment melanin which protects cell DNA from UV light damage
What are the 2 main hormones released by the posterior pituitary? (2)
ADH, oxytosin