Anxiolytics/hypotics Flashcards
Benzos not metabolized by liver for chronic alcoholics and liver disease
Lorazepam
Oxazepam
Temazepam
Anxiolytic uses
Anxiety Muscle spasms Seizures Sleep disorders Alcohol withdrawal Anesthesia induction
BDZs plus alcohol
Respiratory depression and death
Long acting half life >20 hours
Diazepam
Clonazepam
Long acting BDZ
Rapid onset
Detox from alcohol or sedative hypnotics anxiolytics and for seizures
Less for anxiety lately
Diazepam Valium
Long acting BDZ
Anxiety and panic attacks
Avoid in renal dysfunction
Once daily dosing
Clonazepam Klingon
Intermediate acting BDZ half life 6-20 hours
Alprazolam Xanax
Lorazepam Ativan
Oxazepam serax
Temazepam restoril
Intermediate BDZ
Anxiety and panic attacks
Short onset
Euphoria and abuse potential
Alprazolam xanx
Intermediate BDZ Panic attacks Alcohol and sedative-hypnotic-anxiolytics detox Agitation Not metabolized by liver
Lorazepam Ativan
Intermediate BDZ
Alcohol and sedative hypnotic anxiolytics detox
Not metabolized by liver
Oxazepam serax
Intermediate BDZ
Decreasing use for insomnia
Dependance
Not metabolized by liver
Temazepam restoril
Short acting BDZ
Insomnia
Medical and surgical setting
Triazolam halcion
Short acting BDZ
Medical surgical
Midalzolam versed
BDZ over dose
Flumazenil
Reverses benzos receptor agonist
Too quick life threatening
BDZ SE
Drowsiness Impaired intellectual function Reduced motor coordination Anterograde amnesia Withdrawal can be life threatening and cause seizures Toxicity respiratory depression