Antipsychotics (QTc interval) Flashcards

1
Q

Normal

A

Men<440

Women<440

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2
Q

Borderline

A

Men440-450

Women440-460

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3
Q

Prolonged

A

Men>450

Women>460

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4
Q

Antipsychotics with low QTC

A

Aripiprazole is believed to have no effect on the QTc interval. Olanzapine is suggested by the Maudsley Guidelines as an alternative.

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5
Q

Haloperidol

A

Effect on QTc intervalHigh

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6
Q

Pimozide

A

Effect on QTc intervalHigh

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7
Q

Quetiapine

A

Effect on QTc intervalModerate

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8
Q

Chlorpromazine

A

Effect on QTc intervalModerate

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9
Q

Zotepine

A

Effect on QTc intervalModerate

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10
Q

Zipasidone

A

Effect on QTc intervalModerate

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11
Q

Amisulpride

A

Effect on QTc intervalLow

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12
Q

Clozapine

A

Effect on QTc intervalLow

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13
Q

Olanzapine

A

Effect on QTc intervalLow

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14
Q

Risperidone

A

Effect on QTc intervalLow

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15
Q

Aripiprazole and paliperidone

A

Effect on QTc intervalNone

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16
Q

High cardiac risk antipsychotics

A

Both thioridazine and droperidol have been removed from the UK market due to their effect on the QTc interval.