Antipsychotics (QTc interval)

Question 1

Normal

Answer 1

Men<440

Women<440

Question 2

Borderline

Answer 2

Men440-450

Women440-460

Question 3

Prolonged

Answer 3

Men>450

Women>460

Question 4

Antipsychotics with low QTC

Answer 4

Aripiprazole is believed to have no effect on the QTc interval. Olanzapine is suggested by the Maudsley Guidelines as an alternative.

Question 5

Haloperidol

Answer 5

Effect on QTc intervalHigh

Question 6

Pimozide

Answer 6

Effect on QTc intervalHigh

Question 7

Quetiapine

Answer 7

Effect on QTc intervalModerate

Question 8

Chlorpromazine

Answer 8

Effect on QTc intervalModerate

Question 9

Zotepine

Answer 9

Effect on QTc intervalModerate

Question 10

Zipasidone

Answer 10

Effect on QTc intervalModerate

Question 11

Amisulpride

Answer 11

Effect on QTc intervalLow

Question 12

Clozapine

Answer 12

Effect on QTc intervalLow

Question 13

Olanzapine

Answer 13

Effect on QTc intervalLow

Question 14

Risperidone

Answer 14

Effect on QTc intervalLow

Question 15

Aripiprazole and paliperidone

Answer 15

Effect on QTc intervalNone

Question 16

High cardiac risk antipsychotics

Answer 16

Both thioridazine and droperidol have been removed from the UK market due to their effect on the QTc interval.