Antidepressants (tricyclic) Flashcards

1
Q

Secondary amines include:-

A

Desipramine
Nortriptyline
Protriptyline
Amoxapine

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2
Q

Tertiary amines include

A
Amitriptyline
Lofepramine
Imipramine
Clomipramine
Dosulepin (Dothiepin)
Doxepin
Trimipramine
Butriptyline
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3
Q

Common side-effects of TCAs include:-

A
drowsiness
dry mouth
blurred vision
constipation
urinary retention
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4
Q

Choice of tricyclic

A

low-dose amitriptyline is commonly used in the management of neuropathic pain and the prophylaxis of headache (both tension and migraine)
lofepramine has a lower incidence of toxicity in overdose
amitriptyline and dosulepin (dothiepin) are considered the most dangerous in overdose

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