Antipsychotics Flashcards
1
Q
Mechanism of action (SGA)
A
RISPERIDONE is a newer atypical/second generation neuroleptic and is more selective than the older typical neuroleptics.
2
Q
Risperidone can bind to..?
A
dopamine D2, 5-HT2, and a” adrenergic receptors in the brain
3
Q
Atypical neuroleptics
A
which have little or noe affinity for D1 receptors, do not exhibit some of the side effects associated with D1 antagonism that the older neuroleptics have.
4
Q
Main indications
A
psychotic states
bipolar disorder
Violent behavior
(de er fremhevet i rødt i pwerpointen)
5
Q
Treatment guideline (acute treatment)
A
- Often higher doses
- Multiple doses administrer daily
- Couple of weeks
- mono therapy vs polytherapy
6
Q
Treatment guideline (maintenance treatment)
A
- usually lower dose
- can last for years
- once daily administration
- often monotherapy
7
Q
Treatment guideline (long acting depot medication)
A
- improves adherence to treatment
