Antipsychotics Flashcards
Block dopamine receptors in striatum, leading to parkinson-like symptoms
Haloperidol and chlorpromazine
These are effective against positive symptoms of psychosis but not the negative symptoms of psychosis
First gen antipsychotics:
Haloperidol and Chlorpromazine
Cause tardive dyskinesia
Haloperidol and chlorpromazine
Work by blocking all dopamine receptors in the brain and D2 receptors in the limbic system. They lower DA levels resulting in worse negative symptoms
Haloperidol and chlorpromazine
Antipsychotics that block D2 receptors and serotonin receptors
2nd generation antipsychotics
The second generation antipsychotic that’s most effective but can cause agranulosis
Clozapine
Increase lipid levels and can cause weight gain
Olanzapine
Can increase risk of type 2 diabetes
SGA
What are all of the first generation antipsychotics?
Chlorpromazine (thorazine)
Haloperidol (Haldol)
What are all of the second generation antipsychotics
Clozapine (clozaril) Risperidone (risperdal) Olanzapine (Zyprexa) Quetiapine (Seroquil) Aripiprazole (abilify)
These are effective against the positive AND negative symptoms of psychosis.
SGA