Antipsychotic drugs Flashcards
psycho therapeutic drugs
anti psychotic
antidepressant
mood stabilizers
CNS stimulants
Schizophrenia
Chrominc sever mental disorder that affect how peopl think,feels and behaves
2 symptoms of Schizophrenia
positive and negative
Positive symptoms of schizophrenia
hallucinations
delusions
though and movement disorganizations
negative symptoms of schizophrenia
decreased feeling of pleasure
apathy
withdrawal
reduced speaking
postive effect is dure to
increased DA activity in the mesolimbic system
negativ eeffect is due to
decreased activity in the mesolimbic and mesocortical system
Dopamine hypothesis
Schizophrenia is due to the abnormalities in the DA NT in the mesocortical and mesolimbic system
drugs that work on schezophrenia
are the ones that block the D2 receptor
drugs that induce DA relsease
incuces psychosis
Anti psychotic drugs
typical and atypical
typical
older \+ve symptoms potent blocker of D2 also blocks alpha 1,H1,muscuranic receptor 5HT2 receptor
Atypical
newer
-ve symptoms are relieved
blocks 5HT receptor than D2 receptor
Names of typical APD
Halperidol
fluphenazine
clorpromazine
thioridazine
higle potent TAPD
Thioridazine