Antipsychotic drugs Flashcards

1
Q

psycho therapeutic drugs

A

anti psychotic
antidepressant
mood stabilizers
CNS stimulants

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2
Q

Schizophrenia

A

Chrominc sever mental disorder that affect how peopl think,feels and behaves

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3
Q

2 symptoms of Schizophrenia

A

positive and negative

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4
Q

Positive symptoms of schizophrenia

A

hallucinations
delusions
though and movement disorganizations

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5
Q

negative symptoms of schizophrenia

A

decreased feeling of pleasure
apathy
withdrawal
reduced speaking

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6
Q

postive effect is dure to

A

increased DA activity in the mesolimbic system

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7
Q

negativ eeffect is due to

A

decreased activity in the mesolimbic and mesocortical system

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8
Q

Dopamine hypothesis

A

Schizophrenia is due to the abnormalities in the DA NT in the mesocortical and mesolimbic system

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9
Q

drugs that work on schezophrenia

A

are the ones that block the D2 receptor

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10
Q

drugs that induce DA relsease

A

incuces psychosis

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11
Q

Anti psychotic drugs

A

typical and atypical

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12
Q

typical

A
older
\+ve symptoms
potent blocker of D2
also blocks alpha 1,H1,muscuranic receptor
5HT2 receptor
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13
Q

Atypical

A

newer
-ve symptoms are relieved
blocks 5HT receptor than D2 receptor

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14
Q

Names of typical APD

A

Halperidol
fluphenazine
clorpromazine
thioridazine

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15
Q

higle potent TAPD

A

Thioridazine

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16
Q

least potent TAPD

A

halperidol

17
Q

therapy

A

1-3 weeks

1-3week for the dopamine inhibition of neuron

18
Q

ADR of TAPD

A
blocks
D2-Extrapyramidal effect
tardrive dyskinesea
akathesia
dystonia
peudoparkinsonism
H1-sedation
muscurainc-anticholinegic effect
alpha 1 receptor-orthostatic hypotension