Adrenoceptor agonist Flashcards

1
Q

Adrenoceptor agonist

A

drugs that binds with adrenoceprtor receptors and causes physiological changes

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2
Q

adrenoceptor receptors are

A

alpha and Beta
alpha1 and 2
beta 1 and 2

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3
Q

alpha 1

A

contraction of smooth muscle/exocrine gland/neuronal excitation

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4
Q

alpha 2

A

inhibits NE release

CNS effect

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5
Q

Beta 1

A

increase renin secretion
increase HR
increase contractility and conduction

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6
Q

Beta 2

A

bronchodialation
relaxation of smooth muscle
glycogenolysis

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7
Q

3 types of adrenoceptor agonist

A

Direct Catecholamine
Direct noncatecholamine
indirect
mixed

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8
Q

Direct Catecholamine 1

A

Dobutamine

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9
Q

Dobutamine

A

B1,B2

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10
Q

Direct catecholamine 2

A

Dopamine

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11
Q

Dopamine

A

A2

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12
Q

Direct catecholamine 3

A

Epinephrine

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13
Q

Epinephrine

A

b1,b2,a1,D1

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14
Q

Direct catecholamine 4

A

Noepinephrine

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15
Q

norepinephrine

A

a1

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16
Q

Direct catecholamine 5

A

isoproterenol

17
Q

isoproterenol

A

b1,b2

18
Q

Direct noncatecholamine 1

A

albuterol

19
Q

Albuterol

A

b2

20
Q

direct noncatecholamine 2

A

clonidine

21
Q

Clonidine

A

a2

22
Q

direct noncatecholamine 3

A

midodrine

23
Q

midodrine

A

a1

24
Q

Direct catecholamine 4

A

oxymetazoine

25
Q

oxymetazoine

A

a1

26
Q

direct noncatecholamine 5

A

phenylephrine

27
Q

phenylephrine

A

a1

28
Q

direct noncatecholamine 6

A

terbutaline

29
Q

Terbutaline

A

B2

30
Q

Indirect acting adrenceptror agonist

A

amphetamine/cocaine

31
Q

amphetamine

A

increase NE release

32
Q

cocaine

A

Inhibits NE uptake

33
Q

mixed acting adrenoceptor agonist

A

Ephedrine/pseudoephedrine

34
Q

Ephedrine

A

A1 receptor/increase synaptic release of NE

35
Q

Pseudoephedrine

A

A1 receptor/increase synaptic release of NE