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SEM 3 Drugs > Antiprotozoal Drugs > Flashcards

Antiprotozoal Drugs Flashcards

1
Q

Paromomycin

A

MOA: eradicates cyst with a luminal amebicide

amebiasis

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2
Q

Metronidazole,
Tetracycline

A

MOA: kills trophozoites

amebiasis (extraintestinal)

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3
Q

Nitazoxanide

A

MOA: metabolizes to form tizoxanide
- interferes with pyruvate

Intestinal protozoa
- Giardiasis (Giardia sp.)

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4
Q

Sodium Stibogluconate

A

MOA: inhibits DNA synthesis

Leishmaniasis
- Leishmania sp.

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5
Q

Suramin

A

MOA: non-specific enzyme inhibition

Trypanosoma brucei sp.
- 1st stage

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6
Q

Melarsoprol

A

MOA: inhibits enzymes

Tryponosoma brucei sp.
- 2nd stage

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7
Q

Nifurtimox

A

MOA: increases oxidative stress
- produces free radicals

Typanosoma cruzi

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SEM 3 Drugs (9 decks)

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