Antimicrobiral Agents 5.2 Flashcards

1
Q

When is prophylactic use of antibiotics indicated?

A

Peri-operatively
Asplenia (long term)
Short term use eg for meningitis contacts, people very susceptible to UTIs

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2
Q

Why can tetracyclines not be used in pregnant women or in children?

A

As they discolour teeth in foetus’ and infants

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3
Q

What are some common ADRs to Abx?

A
Diarrhoea (as normal flora also killed)
Vomiting
Fever
Nausea
Allergic reactions (rash and anaphylaxis)
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4
Q

Which classes of antibiotics target cell wall synthesis?

A

Beta lactams

Glycopeptides

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5
Q

Which classes of antibiotics target protein synthesis?

A

Aminoglycosides
Tetracyclines
Macrolides

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6
Q

Which classes of antibiotics target DNA synthesis?

A

Quinolones

Folic acid antagonists

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