Antimicrobiral Agents 5.2 Flashcards
1
Q
When is prophylactic use of antibiotics indicated?
A
Peri-operatively
Asplenia (long term)
Short term use eg for meningitis contacts, people very susceptible to UTIs
2
Q
Why can tetracyclines not be used in pregnant women or in children?
A
As they discolour teeth in foetus’ and infants
3
Q
What are some common ADRs to Abx?
A
Diarrhoea (as normal flora also killed) Vomiting Fever Nausea Allergic reactions (rash and anaphylaxis)
4
Q
Which classes of antibiotics target cell wall synthesis?
A
Beta lactams
Glycopeptides
5
Q
Which classes of antibiotics target protein synthesis?
A
Aminoglycosides
Tetracyclines
Macrolides
6
Q
Which classes of antibiotics target DNA synthesis?
A
Quinolones
Folic acid antagonists