13.1: Drugs Affecting Acid Secretion Flashcards
1
Q
Which cells in the stomach are responsible for gastric acid secretion?
A
Parietal cells
2
Q
Why are H2 antagonists more effective to reduce stomach acid secretion than ACh inhibitors or gastrin inhibitors?
A
As H2 antagonists inhibit all stimulation (from gastrin, ACh and histamine)
3
Q
How do alginates work?
A
Form a raft to protect the oesophagus from acid reflux and to neutralise stomach acid
4
Q
How long are PPIs/ H2 antagonists given for to treat a peptic ulcer?
A
6 weeks to allow time for the ulcer to heal
5
Q
What type of drug is ranitidine?
A
H2 antagonist
6
Q
What is the H Pylori triple therapy?
A
Clarithromycin
Amoxicillin
PPI
