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Infectious Disease: Unit 1 > Antimicrobials: Spectrum of Action > Flashcards

Antimicrobials: Spectrum of Action Flashcards

1
Q
A
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2
Q

Prototypical Penicillins

A

Narrow: Gram + / - Cocci, Gram + Rods, Spirochetes

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3
Q

Extended Spectrum Penicillins

A

Broader than PenG/V, includes more Gram + cocci and gram (-) rods

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4
Q

Penicillinase Resistant Penicillins

A

Narrow: MSSA

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5
Q

Anti-Pseuodomonal Penicillin

A

Extended spectrum: Amoxcillin + pseudomonas

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6
Q

Penicillin + ß lactamase inhibitor. Sulbactam is another inhibitor.

A

Same as amoxicillin, but Resists ß lactamases

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7
Q

Cephalosporins: Penicillinase resistant

A

Gram (+) Cocci , Gram (-) Rods.

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8
Q

Carbapenems. Beta lactamase resistant.

A

Wide Spectrum. Gram (+) cocci, Gram (-) rods, anaerobes. Reserved for multi drug resistant organisms

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9
Q

Monobactams

A

Narrow: Aerobic Gram (-) Rods Only

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10
Q

Vancomycin

A

Narrow: Gram (+) Cocci, Anaerobes

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11
Q

Macrolides. MacroLungs

A

Gram (+) Cocci, Atypical pneumonias, URI, STD

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12
Q

Lincomycin

A

Narrow: gram (+) Cocci, Anaerobes in lung abscesses and aspiration pneumonia

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13
Q

Synthetic Agents

A

Meningitis + intracellular

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14
Q

Streptogramins

A

Excellent gram (+) and atypical, reserve for use in MDR gram (+)

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15
Q

Oxazolidinones

A

Excellent gram (+) but save as reserve for MDR organisms

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16
Q

Tetracylines

A

Broad: gram (+) / (-), atypical, intracellular

17
Q

Aminoglycosides

A

Aerobic Gram (-) Rods

18
Q

Metronidazole

A

Anaerobes & Protozoa

19
Q

Fluoroquinolones. Nalidixic acid is a quinolone. Fluoroquinolones tend to end in -oxacin

A

Gram (-) , Atypical, soft tissue infections, UTI, bone

20
Q

Sulfonamides

A

Broad: gram (+) / (-), protozoa. Used for UTIs, pneumonia, otitis media, sinusitis.

21
Q

Miscellaneous

A

Medium spectrum normally used for E. Coli UTIs

22
Q

Antituberculuar Agents

A

Broad Spectrum, Meningitis, endocarditis for prosthetic valves, leprosy, TB

23
Q

Narrow spectrum antibiotics

A
  • Bacitracin
  • Clindamycin
  • Metronidazole
  • Penicillin G, V
  • Penicillinase-resistant penicillins
  • Vancomycin
  • Monobactams
  • Polymyxins, Daptomycin
24
Q

Extended Spectrum Antibiotics

A
  • Aminoglycosides
  • Cephalosporins
  • Extended-spectrum penicillins
  • Fluoroquinolones
  • Carbapenems
  • Macrolides
  • Streptogramins
25
Q

Broad Spectrum Antibiotics

A
  • Chloramphenicol
  • Sulfonamides
  • Tetracycline
  • Trimethoprim

Infectious Disease: Unit 1 (17 decks)

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