Antimicrobials: Pharmacokinetic properties Flashcards by Caitlin Heim | Brainscape

Q

Hepatic Elimination/important metabolism

A

*C**lindamycin, chloramphenicol
*R**ifampin
*I**soniazid
*M**etronidazole
*E**rythromycins
*S**ulfonamides, streptogramins

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Q

Antibiotics with poor oral absorption

A

aminoglycosides

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Q

Antibiotics w/good/widespread distribution

A

3rd gen. cephalosporins: Ceftriaxone, Ceftazidime, Cefdinir
4th gen. cephalosporins: Cefepime

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Q

Metronidazole: Pharmacokinetics

A

high and rapid absorption (oral, parenteral, topical)
excellent distribution
renally excreted, but metabolism can be affected by other drugs
M in CRIMES

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