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Path > Antimicrobials > Flashcards

Antimicrobials Flashcards

1
Q

Protein synthesis inhibition

A

Aminoglycosides- gentamicin

Tetracyclines-doxy

Macrolides- erythromycin

Chloramphenicol- eye drops

Oxazolidinones - linezolid

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2
Q

DNA synthesis inhibition

A

Fluoroquinolones- ciprofloxacin

Nitroimidazoles- metronidazole

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3
Q

RNA synth inhibition

A

Rifamycin- rifampicin

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4
Q

Cell membrane toxin

A

Polymyxin- colistin

Cyclic lipopeptide- daptomycin

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5
Q

Inhibit folate metabolism

A

Sulphonamides- sulphamethoxazole

Diaminopyrimidines- trimethoprim

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6
Q

Beta lactams-
Examples
Indications

A

Penicillins- benzylpenicillin
Cephalosporins- ceftriaxzone
Carbapenems- meropenem

Gram +ves

Gram -ves- 3rd gen cephs and carbapenems

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7
Q

Tetracyclines
Eg
Indication

A

Doxy

Intracellular- chlamydia

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8
Q

Macrolides
Eg
Indication

A

Erythromycin

Gram +ve in pen allergy

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9
Q

Chloramphenicol

A

Eye drops

Bacterial conjunctivitis

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10
Q

Fluoroquinolones
Eg
Indication

A

Ciprofloxacin

Gram negative

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11
Q

Nitroimidazole
Eg
Indication

A

Metronidazole

Anaerobes + protozoa

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12
Q

Rifamycin
Eg
Indication

A

Rifampicin

Mycobacterium- used in TB

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13
Q

Cyclic lipopeptide
Eg
Indication

A

Daptomycin

Gram +ve, MRSA + VRE

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14
Q

Sulphonamides
Eg
Indication

A

Sulphamethoxazole

PCP (with trimethoprim- co-trimaoxazole)

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15
Q

Diaminopyrimidines
Eg
Indication

A

Trimethoprim

UTI

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16
Q

Cell wall synthesis inhibition

A

Beta lactams- penicillins, cephalosporins, carbapenems

Glycopeptides- vancomycin

17
Q

Aminoglycosides
Eg
Indications

A

Gentamicin

Gram -ve sepsis

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