Antimicrobials 2

Question 0

What is zanamivir used for?

Answer 0

Influenza A and B - decreases symptom duration if used within 48 hours of onset

Question 1

How do amantidine, zanamivir and immunoglobulins work?

Answer 1

By preventing the virus from entering or leaving the cell

Question 2

How dose acyclovir work and what is it used for?

Answer 2

HSV, VZV - works via TK to induce synthesis of false DNA

Selectively toxic

Question 3

Under what drug class are acyclovir and ganciclovir?

Answer 3

Nucleosides/nucleotide analogues

Question 4

What is ganciclovir used for?

Answer 4

Severe CMV infections in an immunocompromised host

Question 5

Why is CMV resistant to aciclovir but not ganciclovir?

Answer 5

CMV doesn’t code for TK

Question 6

What are antiretrovirals also called?

Answer 6

NRTIs - nucleotide reverse transcriptase inhibitors

Question 7

Give an example of a NRTI?

Answer 7

Tenofovir

Question 8

What is zidovudine?

Answer 8

Oral NRTI for AIDS

Question 9

What is zanamivir otherwise known as?

Answer 9

Relenza

Question 10

What is oseltamivir otherwise known as?

Answer 10

Tamiflu

Question 11

What are zanamivir (Relenza) and oseltamivir (Tamiflu)?

Answer 11

Neuraminidase inhibitors used for flu

Question 12

What is indinavir?

Answer 12

Protease inhibitor

Question 13

What method is used to determine drug susceptibility via culture?

Answer 13

Kirby-Bauer method