Antimicrobial Pharmacology session 1 Flashcards

1
Q

Prontosil is against which organisms?

A

strep and staph

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2
Q

What does Prontosil make in the body?

A

sulfonamide

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3
Q

What sulfonamide does?

A

prevent the synthesis of folic acid in bacteries

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4
Q

What do we use for chronic prostatitis?

A

fluoroquinolone

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5
Q

Optimum concentration

A

4 times more than the standard amount

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6
Q

MIC

A

minimum inhibitory concentration

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7
Q

MBC

A

minimum bactericidal concentration

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8
Q

strip or targigi?

A

strip is better because the amounts are closer and the results are better

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9
Q

معیار اصلی در دسته بندی آنتی بیوتیک ها

A

ساختاری که دارو در باکتری به آن اثر می گذارد

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10
Q

Antibiotics that affect the folic acid synthesis

A

trimethoprim

sulfonamide

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11
Q

Antibiotics that affect 50S protein synthesis

A

erythromycin
chloramphenicol
clindamycin

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12
Q

Antibiotics that affect 30S protein synthesis

A
tetracycline
spectinomycin
streptomycin
gentamycin
tobramycin
amikacin
aminoglycosides
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13
Q

Antibiotics that affect DNA and RNA

A

quinolone

rifampin

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14
Q

drugs that avoid cell wall synthesis are?

A

bactericide

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15
Q

vancomycin is?

A

glycopeptide

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16
Q

Telavancin is made up of?

A

vancomycin

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17
Q

Dalbavancin is made up of?

A

teicoplanin

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18
Q

Colistin

A

has lots of side effects but is used for some severe cases

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19
Q

Cell-membrane related drugs

A

daptomycin and polymyxin

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20
Q

aplastic anemia

A

chloramphenicol

21
Q

جایگزینی به جای تتراسایکلین در باردارها

A

chloramphenicol

22
Q

دارویی با طیف گسترده و باکترواستاتیک

A

Tetracycline

23
Q

دارویی با طف گسترده و باکتریوساید

A

Carbapenem

24
Q

Clindamycin is effective on?

A

gram-positive non-O2

25
Q

Drugs in the group of macrolides

A

erythromycin
clarithromycin
azithromycin
spiramycin

26
Q

anti-inflammation effects?

A

azithromycin

27
Q

To treat toxoplasmosis in pregnancy

A

spiramycin

28
Q

To treat helicobacter pylori

A

clarithromycin

29
Q

Aminoglycosides are effective on?

A

gram-negative and O2

30
Q

how can we use aminoglycosides for gram positives?

A

with B-lactams

31
Q

سوزاک؟

A

spectinomycin (only used for these cases)

32
Q

The main treatment of Gonorrhea?

A

B-lactams but for replacement, we use spectinomycin

33
Q

Streptogramins?

A

quinupristin and dalfopristin

34
Q

Treatment of penicillin-resistant streptococci pneumonia & vancomycin-resistant staph

A

Linezolid

35
Q

Protein synthesis inhibitor but uses tRna

A

Mupirocin

36
Q

Drugs that affect nucleic acids

A

rifamycin
fluoroquinolone
rifaximin
fidaxomicin

37
Q

موثر بر سل و جذام و عفونت شدید استاف و درمان مننژیت و بروسلوز؟

A

Rifampin

38
Q

Treatment of chronic prostatitis

A

fluoroquinolone

39
Q

درمان اسهال مسافرتی

A

rifaximin

در روده به مدت طولانی باقی می ماند

40
Q

Antimetabolites

A
sulfonamide (bacteriostatic)
trimethoprim
pyrimethamine
proguanil
methotrexate
41
Q

To treat toxoplasma ghondi

A

sulfadiazine with pyrimethamine

42
Q

Only effective on human reductase

A

Methotrexate

43
Q

Metronidazole

A

non-O2 and single cells

44
Q

Reasons we use antibiotics

A

prophylaxis

treat

45
Q

Empirical

A

give drugs for a variety of infections

46
Q

definitive

A

give drug for specific type of infection

47
Q

درمان پنومونی اکتسابی از جامعه

A

levofloxacin

48
Q

درمان پیلونفریت

A

ceftriaxone