Antimicrobial Coverage Flashcards
1
Q
Antimicrobials with Gram Positive Coverage
A
- PCNs (all families)
- Cephalosporins (all generations)
- Vanc
- Dapto
- Zyvox
- Cleocin
- Quinupristin Dalfopristin (Synercid)
- Tetracyclines
- Chloramphenicol
- Telavancin
- TMP/SMZ
- FQs (except cipro)
- Macrolides
- Carbapenems
- Tigecycline
2
Q
Agents with MRSA Coverage
A
- Vanc
- Dapto (not lung)
- Zyvox
- Ceftaroline fosamil
- Telavancin
- Tigecycline
- Dalbavancin (skin)
- Oritavancin (skin)
- TMP/SMZ (CA-MRSA)
- Doxycycline (CA-MRSA)
- Cleocin (CA-MRSA)
- Synercid
3
Q
Enterococcal Coverage
A
- Vanc
- Carbapenem (not VRE)
- Dapto (VRE; cidal)
- Zyvox (VRE; static)
- Synercid (VRE; cidal; toxic)
- Chloramphenicol (VRE; toxic)
- Telavancin (activity but limited clinical data)
- Tigecycline (activity but limited clinical data)
- Nitrofurantoin (UTIs only)
4
Q
Gram Negative Coverage
A
- PCNs (Ureido > Amino)
- 2nd, 3rd, 4th generations
- Carbapenems
- Aztreonam
- Aminoglycosides
- FQs
- TMP/SMZ
- Tigecycline
- Polymyxin B, Colistin
5
Q
Pseudomonas Coverage
A
- Zosyn
- Cefepime, Ceftazidime/avibactam, Ceftolozane/tazobactam
- Carbapenems (not ertapenem)
- Cipro, Levaquin (not moxi)
- Aminoglycosides
- Aztreonam
- Polymyxin B, Colistin
6
Q
Anaerobic Coverage
A
- Flagyl
- Beta-lactam/Beta-lactamase inhibitors (pip/tazo, amp/sul)
- Cefoxitin, Cefotetan
- Carbapenems
- Cleocin
- Moxi
- Tigecycline
- Chloramphenicol
7
Q
Atypicals
A
- FQs (cipro has weaker atypical coverage than the rest)
- Macrolides (Zithromax, Clarithromycin, Erythromycin)
- Tetratcyclines (doxycycline, tetracycline, tigecycline)
