ANTIMICROBIAL (ANTIBIOTICS) Flashcards
Chemical substances produced by a microorganism with the capacity to inhibit other microorganisms.
Antimicrobials (antibiotics)
Destroy/kill the organism.
Antimicrobials (antibiotics)
A spectrum that is effective against a limited number of pathogens.
Narrow Spectrum
Bacitracin, clindamycin, dapsone, erythromycin, gentamicin, isoniazid, polymyxin B and vancomycin
(spectrum)
Narrow Spectrum
A spectrum that destroy different kinds of organism.
Broad Spectrum
PIGBEDCV — means
Polymyxin B
Isoniazid
Gentamicin
Bacitracin
Erythromycin
Dapsone
Clindamycin
Vancomycin
Ampicillin, cephalosporin, chlorampenicol, ciprofloxacin, rifampicin, sulfonamines, trimethoprim and tetracyclin
(spectrum)
Broad Spectrum
CARST — means
Cephalosporin, Chlorampenicol, Ciprofloxacin
Ampicilin
Rifampin
Sulfonamines
Trimethoprim and Tetracyclin
3 Classification of Drugs
Natural Drugs
Semisynthetic Drugs
Synthetic Drugs
A drugs produced by bacteria or fungi.
Natural Drugs
A drugs that is chemically modified natural drugs with added extra chemical groups.
Semisynthetic Drugs
Ampicillin, carbenicillin and methicilli (drugs)
Semisynthetic Drugs
A drugs that chemically produced drugs.
Synthetic Drugs
Sulfonamides, trimethoprom, chloramphenicol, cifrofloxacin, isoniazid, dapsone.
(drugs)
Synthetic Drugs
Is the lowest concentration of a drug that “inhibits” bacterial growth.
Minimal inhibitory concentration (MIC)
Is the lowest concentration of drug that “kills” bacterial growth.
Minimal lethal concentration (MLC)
It is the ratio of the toxic dose to the therapeutic dose.
Therapeutic index
The higher the therapeutic index, the more effective is what agent?
Chemotherapeutic agent
Action of antimicrobials
Inhibiting cell wall synthesis
Inhibiting CHON synthesis
Inhibiting N.A synthesis
Destroying the cell membrane
Inhibiting essential metabolites
2 kinds of Penicillin
Beta lactamase resistant penicillin
Broad spectrum penicillin