Antihistamines

Question 1

Reduces lactation (contraindicated in breast feeding)

Answer 1

Diphenhydramine

Question 2

Anti-emetic anti-histamine

Answer 2

Promethazine

Question 3

Antihistamine associated with photosensitivity

Answer 3

Promethazine

Question 4

Antihistamine used for morning sickness

Answer 4

Doxylamine

Question 5

Antihistamine that cannot be taken with fruit juice (transported by OATPs)

Answer 5

Fexofenadine

Question 6

Second generation anti-histamine that is still sedating

Answer 6

Cetirizine

Question 7

Used for insomnia

Answer 7

Diphenhydramine

Promethazine

Question 8

Used for nausea/vomiting/vertigo prevention

Answer 8

Diphenhydramine
Promethazine
Doxylamine

Question 9

Which use P-glycoprotein transporters

Answer 9

Second generation

Question 10

Which enter the CNS more readily

Answer 10

First generation

Question 11

Metabolized by P450

Answer 11

First generation

Question 12

Metaboized by 3A4

Answer 12

Second generation

Question 13

Which generation causes stimulation in children

Answer 13

First generation (avoid)

Question 14

Which can enter breast milk and cause dysmenorrhia

Answer 14

Fexofenadine

Question 15

Which anti-histamine alters chloride channels inhibiting lung mast cell release of histamine?

Answer 15

Cromolyn Sodium

Question 16

Which is contraindicated in glaucoma?

Answer 16

Diphenhydramine