Antihistamines Flashcards
1
Q
Piriton:Chlorpheniramine (Antihistamine)
A
MOA- competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract.
SE- dizziness, drowsiness;
dry mouth, nose, or throat;
constipation;
blurred vision; or
feeling nervous or restless.
2
Q
Loratidine: Claritin (Antihistamine)
A
MOA- targeting H1 histamine receptors. Loratadine binds to H1 histamine receptors found on the surface of epithelial cells, endothelial cells, eosinophils, neutrophils, airway cells, and vascular smooth muscle cells among others.
SE- headache;
feeling tired or drowsy;
stomach pain, vomiting;
dry mouth; or
feeling nervous or hyperactive.