Antifungal Agents Flashcards
Mycoses AKA
Fungi
Fungi can be broken down into?
Yeasts and molds
Single-cell fungi
Yeasts
Reproduce by budding
Yeasts
Used for baking and alcoholic beverages
Yeasts
Multicellular
Molds
Characterized by long, branching filaments called “hyphae”
Molds
Four general types of mycotic infections
- Cutaneous
- Subcutaneous
- Superficial
- Systemic
Which mycotic infection can be life threatening and usually occur in an immunocompromised host
Systemic
________ may result in overgrowth and systemic infections
Candida albicans
Due to antibiotic therapy, antineoplastics, or immunosuppressants
Candida albicans
Candida albicans in the mouth results in?
- Oral candidiasis
- Thrush
Vaginal candidiasis
Yeast infection
Systemic antifungal agents
- amphotericin B
- fluconazole
- ketoconazole
- itraconazole
Topical antifungal agents
- clotrimazole
- miconazole
- nystatin
What agent is used for thrush?
nystatin
amphotericin B SE
- fever/chills
- headache
- anorexia
- malaise
- nausea
- hypotension
- tachycardia
- muscle and joint pain
- lowered potassium and magnesium levels
amphotericin B is associated with which toxicities?
- Renal toxicity
- neurotoxicity
