Antiepileptic Flashcards
1
Q
Which AED blocks synaptic vesicle 2A protein on the presynaptic terminal of glutamate neuron?
A
Levetiracetam and Brivaracetam
2
Q
What agents open pre and post synaptic K channels?
A
Ezogabine
3
Q
Cannabidiol (Epidiolex) indications and side effects?
A
Indication:
- Dravet syndrome
- Lennox Gastaut syndrome
- Tuberous Sclerosis complex
AE:
- Hepatocellular injury (elevated transaminases)
- need AST/ALT and albumin lelvels pre ad post therapy especially if given with Valproic acid
