antiemetics drugs

Question 1

drugs for nausea and vomiting

Answer 1

ondansetron - 1/2 life 4-9hrs 5HT3 receptor antagonists (first generation)
dexamethasone - corticosteroids
metoclopramide - dopamine receptor antagonists
prochlorperazine - dopamine receptor antagonists
hyoscine - anticholinergics - muscarinic receptor antagonists
aprepitant (oral) and fosaperipitant(iv) - NK 1 repceptor antagonits

Question 2

hyosine used for?

Answer 2

motion sickness

Question 3

ondansetron adverse effects?

Answer 3

chest pain
arrhythmia
bradycardia

Question 4

dexamethasone adverse effects?

Answer 4

bradycardia
Gerd
dyspepsia
hyperglycemia
hypertension
mood swings
Cushing syndrome
oteoporosis

Question 5

metoclopramide adverse effects?

Answer 5

Parkinson symptoms
- rigidity
- tremors
- bradykinesia
increase in porcaltin levels

Question 6

prochlorperazine adverse effects?

Answer 6

Parkinson symptoms
- rigidity
- tremors
- bradykinesia
hypotension

Question 7

hyoscine adverse effects?

Answer 7

blurred vision
dry mouth
sedation

Question 8

for chemo - low nv

Answer 8

ondansetron
dexamethasone
metroclopramide

Question 9

for chemo - moderate nv

Answer 9

ondansetron + dexamethasone

Question 10

for chemo - high nv

Answer 10

ondansetron + dexamethasone+ apreptiant

Question 11

for chemo - delayed nv

Answer 11

prochlorperazine

Question 12

for chemo - anticipatory nv

Answer 12

lorezepam